Meckel's Diverticulum

Preliminary Diagnosis: Meckel's Diverticulum

I. What imaging technique is first-line for this diagnosis

  • Radiopharmaceutical technetium-99m pertechnetate

II. Describe the advantages and disadvantages of this technique for diagnosis of Meckel's diverticulum.


  • Meckel scan is a diagnostic evaluation with high specificity


  • False negative results may be due to lack or minimal gastric mucosa in the diverticulum, rapid washout, or impaired blood supply.

  • False positive results may be due to ectopic gastric mucosa, inflammation, and vascular malformations.

  • Normal small bowel activity can be confused with a Meckel’s diverticulum.

  • Use of ionizing radiation.

III. What are the contraindications for the first-line imaging technique?

  • Pregnancy is a relative contraindication with use of ionizing radiation.

IV. What alternative imaging techniques are available?

  • CT with oral contrast

V. Describe the advantages and disadvantages of the alternative techniques for diagnosis of Meckel's diverticulum.

CT with oral contrast


  • Relatively quick imaging procedures that require minimal patient cooperation and are less susceptible to motion artifact


  • A Meckel’s diverticulum suspected on CT is likely an incidental finding and may be confirmed with a Meckel scan if clinically indicated.

  • CT imaging is not a sensitive test to detect a Meckel’s diverticulum.

  • Findings may be confused with appendicitis.

  • For pregnant women, ultrasound is the first choice of imaging.

VI. What are the contraindications for the alternative imaging techniques?

CT with oral contrast

  • Contraindicated in pregnant women, especially within the first two trimesters

You must be a registered member of ONA to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings


Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs