Human Papillomavirus

HPV Vaccination and Anti-programmed Cell Death 1 Inhibition Improve Survival in Patients With Invasive HPV-16

HPV Vaccination and Anti-programmed Cell Death 1 Inhibition Improve Survival in Patients With Invasive HPV-16

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In this study, researchers sought to determine if use of a tumor specific vaccine would improve the efficacy of PD-1 immune checkpoint inhibition in patients with incurable HPV-16 cancer.

FDA Approves HPV Vaccine for People Through Age 45

FDA Approves HPV Vaccine for People Through Age 45

Updated vaccine designed to prevent cancers and disease caused by nine HPV types

CDC: HPV Vaccination Rates on the Rise Among Adolescents

CDC: HPV Vaccination Rates on the Rise Among Adolescents

Proportion of teens up to date with HPV vaccines also increasing, researchers found.

Failure Rates for HPV Vaccine Higher in HIV-Positive Women, Girls

Failure Rates for HPV Vaccine Higher in HIV-Positive Women, Girls

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Canadian investigators conducted a national observational study in which women and girls living with HIV underwent HPV vaccination.

Primary HPV testing may detect cervical neoplasms earlier and more accurately than cytology

1. In this Canadian, randomized controlled trial, the use of primary HPV testing compared with cytology resulted in a significantly lower likelihood of CIN3+ at 48 months. 2. There was also significantly fewer CIN2+ cases in women screened with HPV testing compared with women who were screened with cytology alone at baseline. Evidence Rating: 1 []

High-certainty Evidence That HPV Vaccines Protect Against Cervical Precancer

High-certainty Evidence That HPV Vaccines Protect Against Cervical Precancer

High-certainty evidence for cervical cancer protection in adolescent girls and young women aged 15 to 26 years.

Incidence, Age at Diagnosis Increasing in HPV-Positive Oropharyngeal Squamous Cell Carcinoma

Incidence, Age at Diagnosis Increasing in HPV-Positive Oropharyngeal Squamous Cell Carcinoma

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A retrospective study demonstrates an increase in HPV16-positive status among patients with OPSCC and a corresponding increase in age at diagnosis.

Age, Race, Sex Affect Survival for Patients With HPV-Associated Cancers

Age, Race, Sex Affect Survival for Patients With HPV-Associated Cancers

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Using a data sample from the CDC National Program for Cancer Registries, investigators determined how demographic factors — age, race, and sex — impact 5-year survival rates for HPV-associated cancers from initial diagnosis until death.

HPV and Cancer (Fact Sheet)

HPV and Cancer (Fact Sheet)

This fact sheet examines possible links between human papillomaviruses (HPVs) and cancer.

Incidence of Invasive Cervical Cancer May Not Be Affected by HIV Status

Incidence of Invasive Cervical Cancer May Not Be Affected by HIV Status

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HIV infection may not have a contributory effect on the incidence of invasive cervical cancer (ICC) in women as they age.

Pembrolizumab Use With CRT Safe in Locally Advanced HNSCC

Pembrolizumab Use With CRT Safe in Locally Advanced HNSCC

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Small study also showed that pembrolizumab does not significant impair radiation or chemotherapy dosing.

HPV Vaccination Has Potential to Substantially Reduce Infections But Improved Uptake Needed

HPV Vaccination Has Potential to Substantially Reduce Infections But Improved Uptake Needed

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In a comparison of vaccinated vs unvaccinated young adults, oral HPV infection prevalence was found to be substantially lower in persons 18 to 33 years who received at least 1 vaccine-dose during the study years.

Education and Coaching Are Necessary to Treat Oropharyngeal Cancers After Chemoradiotherapy

Education and Coaching Are Necessary to Treat Oropharyngeal Cancers After Chemoradiotherapy

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A literature review noted improvements in quality of life after patients were coached and educated following radiotherapy for HPV-associated oropharyngeal cancers.

Presence of Protein E6 Predictive of Oropharyngeal Cancer Risk in HPV16-Infected Persons

Presence of Protein E6 Predictive of Oropharyngeal Cancer Risk in HPV16-Infected Persons

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Protein produced by chronically infected cells in persons with HPV16 infection serves as a biomarker for risk of cancer of the oropharynx.

ASCO Issues Global Guidance for HPV Vaccination for Cervical Cancer Prevention

ASCO Issues Global Guidance for HPV Vaccination for Cervical Cancer Prevention

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ASCO offers global recommendations for HPV vaccination tailored to structural resource levels of regions.

Parental Self-persuasion in Low-Income Groups Improves HPV Vaccination Rates

Parental Self-persuasion in Low-Income Groups Improves HPV Vaccination Rates

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Self-persuasion is more effective than external persuasion for motivating low-income parents to vaccinate their children against HPV.

HPV Vaccination Discussions Need to Focus on Education, Awareness

HPV Vaccination Discussions Need to Focus on Education, Awareness

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The top reasons for not initiating HPV vaccination are necessity, safety, and knowledge, rather than a lack of discussions on sexuality.

Low Incidence of Cervical Cancer for HPV-Negative Women

Low Incidence of Cervical Cancer for HPV-Negative Women

Human papillomavirus (HPV)-negative women have low long-term incidence of cervical cancer and CIN3+, which supports an extension of the cervical screening interval beyond five years for some, according to a study.

Outcomes Are Better for HPV16-Associated Oropharyngeal Cancer, but Not for Other HPV Strains

Outcomes Are Better for HPV16-Associated Oropharyngeal Cancer, but Not for Other HPV Strains

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Patients with oropharyngeal tumors that harbor HPV16 have higher 5-year survival and lower recurrence rates than patients with tumors that harbor other HPV strains or are HPV-negative.

Additional Evidence HPV Vaccine Protects Against Cervical Cancer

Additional Evidence HPV Vaccine Protects Against Cervical Cancer

The vaccine against human papillomavirus (HPV) infection appears even more effective than previously believed and protection appears to occur even when only one or two of the recommended doses are given.

Poor Oral Health Associated With OPSCC Regardless of HPV Status

Poor Oral Health Associated With OPSCC Regardless of HPV Status

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Despite a higher risk for HPV-negative orophayngeal squamous cell carcinoma (OPSCC), poor oral health appears to be associated with OPSCC regardless of HPV status.

HPV Vaccination Program Reduces Cervical Cell Anomalies in Young Women

HPV Vaccination Program Reduces Cervical Cell Anomalies in Young Women

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Fewer cervical cell anomalies were present on cervical cancer screens of young women in Canada who received the HPV vaccine through a school-based program.

CDC: Most HPV-Linked Cancers Are Preventable

CDC: Most HPV-Linked Cancers Are Preventable

Cervical cancer, and oropharyngeal cancers in men, account for most HPV-associated cancers.

More Than HPV Vaccine Uptake Is Needed to Reduce the Burden of HPV-associated Cancers

More Than HPV Vaccine Uptake Is Needed to Reduce the Burden of HPV-associated Cancers

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Although HPV vaccination is expected to decrease the cancer burden from HPV across all racial and ethnic groups, some disparities are expected to persist and widen if their causes are not addressed, including lack of access to screening, timely diagnoses, and treatment.

Canadian Vaccination Programs Encouraged to Extend HPV Vaccine to Males

Canadian Vaccination Programs Encouraged to Extend HPV Vaccine to Males

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An analysis has recommended expanding HPV vaccination programs to include males in Canada because it will help protect them against HPV-related cancers.

ASCO Offers Guidelines for Increasing HPV Vaccine Uptake

ASCO Offers Guidelines for Increasing HPV Vaccine Uptake

Oncologists should raise awareness of HPV-related cancers and role of vaccinations

High-risk HPV Infection Increases Risk for Anal Cancer

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Anal cancer is associated with human papillomavirus (HPV) infection, and some women are at increased likelihood of have both diseases.

Imaging, Physical Examination Find Most Recurrences of HPV-positive Oropharyngeal Cancer

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Posttreatment imaging at 3 months and physical examinations during the 6 months following treatment can detect most recurrences in patients treated with definitive radiation therapy for HPV-associated oropharyngeal cancer.

Serum HPV Antibody Levels May Be a Biomarker for Recurrent HPV-associated Oropharyngeal Cancer

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Among patients treated for oropharyngeal cancers linked to human papillomavirus (HPV) infection, at least 1 HPV-infection antibody could help identify those patients at risk for a recurrence of the cancer.

Initiation of HPV Vaccination Highest Among High-poverty and Majority Hispanic Communities

Initiation of HPV Vaccination Highest Among High-poverty and Majority Hispanic Communities

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Teen girls living in high-poverty and in majority Hispanic communities had the highest rates of having received at least 1 dose of the HPV vaccine compared with those in low-poverty communities and in communities of other racial or ethnic compositions.

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