GLAUCOMA TREATMENTS
Generic Brand Strength Size Form Adult Dose
ALPHA2-AGONISTS
apraclonidine HCl Iopidine 0.5% 5mL, 10mL soln1 1–2 drops 3 times daily
brimonidine 
tartrate
Alphagan P 0.1%, 0.15% 5mL, 
10mL, 
15mL
soln2 1 drop every 8hrs
ALPHA2-AGONIST + BETA-BLOCKER
brimonidine 
tartrate/ timolol maleate
Combigan 0.2%/
 
0.5%
5mL, 10mL soln1 1 drop every 12hrs
BETA-BLOCKERS
betaxolol HCl 0.5% 5mL, 10mL, 15mL soln1 1–2 drops twice daily
Betoptic S 0.25% 2.5mL, 5mL, 10mL, 15mL susp1 1–2 drops twice daily
carteolol HCl 1% 5mL, 10mL, 15mL soln1 1 drop twice daily
levobunolol HCl Betagan 0.5% 5mL, 10mL, 15mL soln1 1–2 drops once or twice daily
metipranolol HCl Optipranolol 0.3% 5mL, 10mL soln1 1 drop twice daily
timolol hemihydrate Betimol 0.25%, 0.5% 5mL, 10mL, 15mL soln1 1 drop twice daily
timolol maleate Istalol 0.5% 5mL soln1 1 drop once daily in the morning
0.25%, 0.5% 5mL, 10mL soln1 Initially 1 drop of 0.25% twice daily; max 1 drop of 0.5% twice daily
Timoptic Ocudose 0.25%, 0.5% 60 soln4
Timoptic-XE 0.25%, 0.5% 2.5mL, 5mL gel-forming soln 1 drop once daily
CARBONIC ANHYDRASE INHIBITORS
acetazo
lamide
Diamox Sequels 500mg 100 sust-rel caps 500mg twice daily
brinzolamide Azopt 1% 2.5mL, 5mL, 10mL, 15mL susp1 1 drop 3 times daily
dorzolamide HCl Trusopt 2% 10mL soln1 1 drop 3 times daily
methazo
lamide
Neptazane 25mg, 50mg 90 tabs 50–100mg twice to three times daily
CARBONIC ANHYDRASE INHIBITOR + ALPHA-AGONIST
brinzo
lamide/ brimonidine tartrate
Simbrinza 1%/0.2% 8mL susp1 1 drop three times daily
CARBONIC ANHYDRASE INHIBITOR + BETA-BLOCKER
dorzolamide HCl/ timolol 
maleate
Cosopt 2%/0.5% 10mL soln1 1 drop twice daily
Cosopt PF 2%/0.5% 0.2mL soln4
CHOLINERGIC (MIOTIC) AGONISTS
carbachol Isopto Carbachol 1.5% 15mL soln1 2 drops up to 3 times daily
3% 15mL, 30mL
pilocarpine HCl Isopto Carpine 1%, 2%, 4% 15mL soln1 2 drops up to 3–4 times daily or more if needed. Heavily pigmented irides: need higher concentrations.
Pilopine HS 4% 4g gel1 Apply ½ inch ribbon in lower conjunctival sac at bedtime
CHOLINESTERASE INHIBITORS
ecothiophate iodide Phospholine Iodide 0.03%, 
0.06%, 0.125%, 0.25%
5mL soln 0.03% soln instilled twice daily.
If being transferred due to unsatisfactory control with pilocarpine, carbachol, epinephrine, etc, use higher strength soln.
PROSTAGLANDIN ANALOGS
bimatoprost Lumigan 0.01%, 0.03% 2.5mL, 5mL, 7.5mL soln1 1 drop once daily in the evening
latanoprost Xalatan 0.005% 2.5mL soln1 1 drop once daily in the evening
tafluprost Zioptan 0.0015% 0.3mL soln4 1 drop once daily in the evening
travoprost Travatan Z 0.004% 2.5mL, 5mL soln3 1 drop once daily in the evening
PROSTANOIDS (DOCOSANOIDS)
unoprostone isopropyl Rescula 0.15% 5mL soln1 1 drop twice daily
SYMPATHOMIMETICS
dipivefrin HCl Propine 0.1% 5mL, 10mL, 15mL soln1 1 drop every 12hrs
NOTES

Key: soln = solution; sust-rel caps = sustained release capsules; susp = suspension

1Contains benzalkonium chloride. May be absorbed by soft contact lenses.

2Contains purite.

3Contains sofZia (boric acid, propylene glycol, sorbitol, zinc chloride).

4Preservative-free.

Not an inclusive list of medications and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling.

(Rev. 8/2017)

This article originally appeared on MPR