|ACUTE OTITIS MEDIA TREATMENTS: NEWBORN−12 YEARS|
|amoxicillin*||Amoxil||drops||50mg/mL||bubble gum|| ≤12wks: Max 30mg/kg/day in 2 divided doses every 12hrs
>12wks (<40kg): 40mg/kg/day in 3 divided doses every 8hrs
Or 45mg/kg/day in 2 divided doses every 12hrs
≥40kg: as adult
Note: The AAP recommends 80−90mg/kg/day in divided doses (this is not an FDA‑approved dose)
|susp||200mg/5mL, 250mg/5mL, 400mg/5mL||bubble gum|
|chew tabs||200mg, 400mg||cherry-banana-peppermint|
|amoxicillin + clavulanate
(clavulanate component in parentheses)
|banana|| <12wks: 30mg/kg/day (of amoxicillin) in 2 divided doses every 12hrs (use 125mg/5mL susp)
≥12wks (<40kg): 45mg/kg/day (of amoxicillin) in 2 divided doses every 12hrs (use 200 or 400mg/5mL susp or 200mg or 400mg chew tabs)
Or 40mg/kg/day (of amoxicillin) in 3 divided doses every 8hrs (use 125 or 250mg/5mL susp, or 250mg or 500mg chew tabs)
≥40kg: 500mg every 12hrs or 250mg every 8hrs
|strawberry cream|| <3mos: Not recommended.
≥3mos (<40kg): 90mg/kg/day in 2 divided doses every 12hrs
≥40kg: use adult formulations
|cherry-vanilla-banana|| <6mos: Not established.
≥6mos: 30mg/kg as a single dose (max 1.5g); or 10mg/kg (max 500mg) once daily for 3 days; or 10mg/kg (max 500mg) once then 5mg/kg (max 250mg) per day for 4 days.
|cefaclor||—||susp||125mg/5mL, 187mg/5mL, 250mg/5mL, 375mg/5mL||strawberry|| <1mo: Not recommended.
≥1mo: 40mg/kg/day in 2 divided doses every 12hrs, or in 3 divided doses every 8hrs; max 1g/day
|cefdinir||—||susp||125mg/5mL, 250mg/5mL||strawberry||<6mos: Not recommended. >6mos: 14mg/kg every 24hrs for 10 days or 7mg/kg every 12hrs for 5−10 days; max 600mg/day|
|strawberry|| <6mos: Not recommended.
6mos−12yrs (<50kg): 8mg/kg once daily or 4mg/kg every 12hrs
>12yrs (>50kg): 400mg once daily
|cefpodoxime||—||susp||50mg/5mL, 100mg/5mL||lemon-creme|| <2mos: Not recommended.
≥2mos: 5mg/kg (max 200mg) every 12hrs for 5 days
|cefprozil||—||susp||125mg/5mL, 250mg/5mL||bubble gum|| <6mos: Not recommended.
>6mos: 30mg/kg/day in 2 divided doses every 12hrs
|N/A||50mg/kg IM once; max 1g|
|cefuroxime||Ceftin4||susp||125mg/5mL, 250mg/5mL||tutti-frutti|| <3mos: Not recommended.
>3mos: 30mg/kg/day in 2 divided doses; max 1g/day
Children who can swallow tablets whole: one 250mg tab twice daily
|cephalexin||Keflex||caps||250mg, 500mg, 750mg||N/A||75−100mg/kg/day in 4 divided doses|
|ciprofloxacin||Otiprio5||otic susp||6%||N/A|| <6mos: Not established.
>6mos: one 0.1mL (6mg) single dose into each affected ear, after effusion suctioning.
|Biaxin||susp||125mg/5mL, 250mg/5mL||fruit-punch|| <6mos: Not established.
>6mos: 7.5mg/kg every 12hrs for 10 days
oxazole (SMX) +
|—||susp||200mg (SMX) +
|cherry, grape|| <2mos: Not recommended.
≥2mos: 8mg/kg of TMP (40mg/kg of SMX) per day in 2 divided doses every 12hrs for 10 days
|trimethoprim||Primsol||soln||50mg/5mL||bubble gum||≥6mos: 10mg/kg daily in 2 divided doses every 12hrs|
Key: drops = oral drops. susp = oral suspension (as supplied or after reconstitution).
* Indicates the drug is available under other brand names not shown here.
1 These formulations are intended to be used in three-times-daily (TID) regimens. Do not substitute plain tabs for chewable tabs.
2 These formulations are intended to be used in twice-daily regimens. Do not substitute plain tabs for chewable tabs.
3 These products should be taken with food.
4 Ceftin susp and Ceftin tabs are not bioequivalent and cannot be interchanged on a mg/mg basis. Ceftin tabs can be taken without regard to meals; Ceftin susp must be taken with food.
5 For intratympanic administration only, in patients with effusion undergoing tympanostomy tube placement.
Not an inclusive list of medications, dosing regimens, formulations, and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. Information on prophylaxis of chronic otitis media infections is not included. Under certain clinical conditions (eg, impaired renal or hepatic function), the dose may need to be adjusted. Unless stated otherwise, otitis media is generally treated for 10−14 days.
This article originally appeared on MPR