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Side-Effect Management

Side-Effect Management

Cancer Management and Research

Preoperative Cachexia Predicts Poor Outcomes in Young Rather Than Elderly Gastric Cancer Patients: A Prospective Study

Background: Cachexia affects nearly 50–80% of cancer patients, and most studies have only focused on elderly patients. We investigated preoperative cachexia in gastric cancer (GC) patients by age group and comprehensively analyzed the impact of preoperative cachexia on the prognosis of GC patients in all age groups.Methods: In total, 575 patients were prospectively analyzed. The effect of…
Cancer Management and Research

A Prospective Study on Urine Alkalization With an Oral Regimen Consisting of Sodium Bicarbonate and Acetazolamide in Patients Receiving High-dose Methotrexate

[Cancer Management and Research] Researchers sought an alternative regimen for urine alkalization in patients receiving high-dose methotrexate. The typical regimen, IV sodium bicarbonate, has been on shortage. This study determined the safety of an oral regimen of sodium bicarbonate and acetazolamide to achieve a urine pH >7, which is necessary for safe administration of high-dose methotrexate.
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