Depressed African American patients with cancer could be more accurately identified if the depression measures used are more culturally sensitive, according to a study published in the Journal of Mental Health (2015;7:1-6).

Case Western Reserve University nurse scientist Amy Zhang, who has long examined quality-of-life issues in patients with cancer, wondered whether depression in African American cancer patients has been under-recognized for treatment.

Accurately assessing depression in cancer patients is difficult in general because the physical symptoms of cancer and depression, which are low energy, lack of sleep, and loss of appetite, are so similar.

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“African American cancer patients are often sicker and have more severe physical symptoms,” said Zhang, PhD, an associate professor at Case Western Reserve’s Frances Payne Bolton School of Nursing in Cleveland, Ohio. “So I wanted to see if something was missing in how and what we were asking patients.”

Among other important implications, identifying and treating depression in cancer patients is critical because those with a more optimistic outlook tend to live longer.

Zhang and her colleagues studied 74 cancer patients (34 depressed and 23 nondepressed African Americans and 17 depressed whites) at a Northeast Ohio medical center, hoping to identify depression symptoms in black patients with cancer through group comparisons.

The participants had diagnoses of early stage breast or prostate cancers within the previous 3 years and were at least 6 months from their last treatment. They were asked a series of open-ended questions to measure depression.

Depressed African American patients reported feeling irritable and wanting to be alone more frequently than nondepressed black patients, which are symptoms not usually described on the diagnostic test for depression. They also reported more insomnia, fatigue, and crying more frequently.

Researchers also found that depressed African American patients reported sad feelings less often than depressed white patients. Many black cancer patients did not use the word depressed to describe how they were feeling, using instead such words as feeling down, gloomy, low, or blue.

“Because we don’t use those words in standardized testing, we could be losing people with depression,” Zhang said.

Their conclusion: Standard psychological tests are mainly based on responses from white patients. Therefore, black cancer patients may benefit from more culturally sensitive depression measures that consider irritability, social isolation, and describing a down mood in ways other than feeling depressed.

Given new clues to depression in black cancer patients may allow clinicians to more accurately diagnose and treat the disorder by asking new questions that specifically target such symptoms, Zhang said.

Next, Zhang hopes to begin testing a larger number of participants to see if using culturally sensitive questions and descriptions of symptoms result in better diagnosis of and treatment for black cancer patients with depression.