Chemo Does Not Improve Long-Term Outcomes in Early-Stage ILC
Chemotherapy does not improve long-term outcomes in patients with early-stage invasive lobular carcinoma, according to a meta-analysis.
News
Long-Acting G-CSF May Reduce FN-Related Hospitalization in DLBCL After R-CHOP
Long-acting G-CSF can reduce the risk of hospitalization related to febrile neutropenia in patients with DLBCL treated with R-CHOP.
Analysis of Sacituzumab Govitecan Shows Manageable Safety Profile in mTNBC
Researchers report on the safety data from the phase 3 ASCENT trial of sacituzumab govitecan in the treatment of metastatic triple-negative breast cancer.
Enfortumab Vedotin Plus Pembrolizumab ‘Promising’ for Untreated Advanced Urothelial Carcinoma
Patients with advanced urothelial carcinoma treated with first-line enfortumab vedotin plus pembrolizumab had a 93.3% disease control rate.
Vaccine-Pembrolizumab Combo Appears Active in HPV+ Advanced Cervical Cancer
Combination treatment with the GX-188E vaccine and pembrolizumab can elicit responses in patients with HPV 16-/18-positive advanced cervical cancer.
Orelabrutinib Plus RCHOP Effective for Extranodal, Non-GCB Diffuse Large B-Cell Lymphoma
The aim of this trial was to evaluate the efficacy and safety of orelabrutinib with RCHOP in patients with extranodal non-GCB DLBCL.
Open-Label Placebo Effective for Cancer-Related Fatigue With Advanced Cancer
Researchers sought to measure outcomes for cancer-related fatigue in patients with advanced cancer treated with open-label placebo, compared with a waitlist control group.
PLM60 Plus Pegaspargase Shows Promise in Extranodal Natural Killer and T-Cell Lymphoma
Researchers sought to determine whether PLM60 with pegaspargase would have efficacy in patients with extranodal natural killer/T-cell lymphoma.
Effects of Timing of ROM Exercise After Breast Cancer Surgery on Outcomes
A report suggests the timing of range-of-motion exercises after breast cancer surgery may affect flexion range of motion without affecting wound outcomes.
Liposomal Irinotecan Improves Upon 5-FU/LV in Refractory Pancreatic Cancer
Adding liposomal irinotecan to 5-fluorouracil and leucovorin can improve outcomes in gemcitabine-refractory, advanced pancreatic cancer, a phase 3 study suggests.
Cladribine Induces Long-Term, Durable Responses in Hairy Cell Leukemia
Researchers sought to determine the long-term efficacy of cladribine in patients with hairy cell leukemia.
Real-World PRO Monitoring in Lung Cancer Lags Outside Clinical Trial Settings
Researchers sought to measure real-world adherence to patient-reported outcomes monitoring as a cancer care metric.
Genomic Features and Anti-CD19 CAR-T Therapy Failure in Large B-Bell Lymphoma
Researchers sought to identify genomic features in patients with large B-cell lymphoma that are linked with anti-CD19 CAR-T therapy.
Cutaneous T-Cell Lymphoma Incidence on the Rise in the United States
The incidence of cutaneous T-cell lymphoma in the United States increased from 2000 to 2018, with an annual percent change of 0.61%.
American Indians, Alaskan Natives Engage in Few Skin Cancer Prevention Behaviors
Researchers at Brigham and Women’s Hospital investigated the skin cancer prevention behaviors of these rarely studied ethnic groups.
Novel Hormonal Therapies for nmCRPC Underused, Data Show
Investigators characterized practice patterns in the first-line treatment of nonmetastatic castration-resistant prostate cancer using real-world data.
Conditioning Regimens Produce Similar Long-Term Outcomes in Newly Diagnosed Multiple Myeloma
Conditioning with MEL200 or BUMEL produced similar outcomes at 7 years.
Besremi Approved for Adults With Polycythemia Vera
Besremi is a monopegylated, long-acting interferon, which exhibits its cellular effects in the bone marrow in polycythemia vera.
Prevalence of Adrenal Tumors Modest Despite Significant Increase in Detection
Researchers sought to understand the significance of increasing detection rates of adrenal tumors due to improved imaging technologies.
Women With Genetic VUS Undergo Breast Cancer Screening Less Frequently
Study results describe how genetic test results influence adherence to breast cancer surveillance recommendations among women with variants of uncertain significance vs those with pathogenic variants.
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