According to a recent study published in JAMA Oncology, researchers at Washington University School of Medicine in St. Louis, Missouri, have developed a noninvasive urine test that screens for kidney cancer.
For the study of the screening method, researchers analyzed urine samples from 720 patients were about to undergo an abdominal CT scan for reasons other than suspicion of kidney cancer, 80 healthy people, and 19 patients previously diagnosed with cancer. The test measured levels of two proteins biomarkers in the urine.
Results showed that none of the 80 healthy people had increased levels of either biomarker and all of the 19 patients with kidney cancer had elevated levels of both. In addition, three of the 720 patients who underwent an abdominal CT scan had increased levels of both proteins; two were confirmed to have kidney cancer.
Ultimately, the protein biomarkers were over 95% accurate in identifying early-stage kidney cancer and the test did not result in any false-positive caused by non-cancerous kidney disease.
Researchers at Washington University School of Medicine in St. Louis have developed a noninvasive method to screen for kidney cancer that involves measuring the presence of proteins in the urine.