The use of statins is associated with a 46% increase in the risk of developing diabetes, a new study published in the journal Diabetologia has shown.
For the study, researchers from the University of Eastern Finland and Kuopio University Hospital in Finland sought to investigate the effects of statin treatment on the risk of type 2 diabetes and blood sugar control in non-diabetic men that participated in the 6-year follow-up of the Metabolic Syndrome in Men (METSIM) study.
Among the 8,749 participants, 625 were diagnosed with new diabetes during the 5.9-year followw-up period.
Results showed that after adjusting for confounding factors, such as BMI, physical activity, alcohol intake, smoking, and beta-blocker and diuretic use, patients who took statins were 46% more likely to develop diabetes compared with those who were not treated with diabetes.
Researchers found that the high-dose simvastatin was associated with a 46% increased risk of developing diabetes compared with 28% increased risk for low-dose simvastatin. High-dose atorvastatin was associated with a 37% increased risk.
New research published in Diabetologia (the journal of the European Association for the Study of Diabetes) shows that use of statins is associated with a 46% increase in the risk of developing diabetes, even after adjustment for confounding factors.