Soy, isoflavone consumption not associated with endometrial cancer risk

the Oncology Nurse Advisor take:

According to a new study published in the journal BJOG, an international journal obstetrics and gynecology, researchers from the National Cancer Center in Tokyo, Japan, have found that soy food/isoflavone consumption is not associated with endometrial cancer risk in Japanese women.

For the study, researchers sought to investigate whether a correlation exists between soy food/isoflavone consumption and endometrial cancer risk because consumption of soy food in Japan is very high while endometrial cancer incidence is very low.

Researchers conducted a prospective cohort study that included 49,121 Japanese women aged 45 to 74 years. Participants completed self-administered food frequency questionnaires that assessed intake of soy foods and isoflavones between 1995 and 1998, followed by a 5-year follow-up survey.

Results showed that during an average follow-up of 12.1 years, there were 112 cases of newly diagnosed endometrial cancer. The researchers found no association between soy food and isoflavone consumption and endometrial cancer risk.