A family history of breast cancer does not influence prognosis for women with breast cancer, according to results of a new large study from UK researchers. Approximately one-quarter of breast cancer cases in developed countries are thought to be hereditary.
The researchers conducted an analysis of the Prospective Outcomes in Sporadic versus Hereditary breast cancer (POSH) study, which included 2,850 women younger than 41 years with a breast cancer diagnosis and were treated in the United Kingdom.
POSH investigators had recorded information on patients’ tumors, treatment, family history of breast/ovarian cancer, and personal characteristics over a 15-year period.
In this study, no significant differences were found in cancer recurrence rates between women with a family history and those with no family history.
Future investigations will focus on the impact of certain gene variants on the effectiveness of different anticancer treatments.
A new large study finds that women who are diagnosed with breast cancer and have a family history of the disease face no worse of a prognosis after treatment than other women with breast cancer.
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