Purpose of this study is to investigate the risk for first depression, assessed as incident hospital contacts for depression and incident use of antidepressants, among women with breast cancer. Women with breast cancer are at long–term increased risk for first depression, including both severe episodes leading to hospital contact and use of antidepressants.

Clinicians should be aware that the risk is highest in women with comorbid conditions, node–positive disease, and age of 70 years or more. The authors found no clear association between type of surgery or adjuvant treatment and risk for depression.

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