HPV types 16 and 18 are associated with about half of penile cancers, researchers in Spain have found. Their systematic review of 31 studies evaluated the prevalence of different HPV types in a total of 1,466 penile cancers. Overall, HPV prevalence in these cases was 46.9 per cent, with just over 60 per cent being associated with HPV 16 and about 13 per cent with HPV 18. Basaloid and warty squamous cell carcinomas were the most frequent HPV-related histological types. The authors estimate that some 7,000 cases of penile cancer could be prevented every year by eradicating HPV 16 and 18.

Miralles-Guri C, Bruni L, Cubilla AL et al. J Clin Pathol 2009;62(10):870-8

Originally published in the December 2009 edition of MIMS Oncology & Palliative Care.