There are several agents for managing cancer cachexia. Megestrol acetate, cannabinoids, corticosteroids and ghrelin are known to affect appetite. Eicosapentaenoic acid (EPA), β-hydroxy-β-methylbutyrate (HMB), thalidomide, corticosteroids and non-steroidal anti-inflammatory drugs are known to affect cachectic mediators or signal pathways. Some drugs, such as megestrol acetate and corticosteroids, exhibit confirmed effectiveness in combating cancer cachexia by randomised controlled trials and systematic reviews. However, until now, there is no identified standard treatment for cancer cachexia.

Herbal medicines have been used widely to treat diverse diseases for thousands of years.

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