A cool pad pillow topper may be useful as an aid to reduce sleep disturbance and frequency and severity of hot flushes in women on endocrine therapy for breast cancer, a recent study published online ahead of print in the journal Supportive Care in Cancer has shown.1
Because women with breast cancer receiving adjuvant endocrine therapy may experience hot flushes and night sweats that may reduce their quality of life, researchers sought to evaluate whether the cool pad pillow topper, a commercial product that promotes improved sleep quality affected by hot flushes, reduces the frequency and/or severity of sleep disturbances.
For the phase 2 study, researchers enrolled 74 pre- and postmenopausal women with breast cancer receiving adjuvant endocrine therapy, such as tamoxifen, who were experiencing hot flushes and insomnia. Patients were randomly assigned to receive standard care with or without the cool pad pillow topper.
Results showed that although sleep quality improved in both groups, it improved almost twice as much in the intervention arm as that of the control arm.
Researchers found that participants in the cool pad pillow topper group experienced significantly greater reductions in hot flushes and depression, but there were no differences in anxiety or quality of life between the 2 treatment arms.
1. Marshall-McKenna R, Morrison A, Stirling L, et al. A randomised trial of the cool pad pillow topper versus standard care for sleep disturbance and hot flushes in women on endocrine therapy for breast cancer [published online ahead of print October 8, 2015]. Support Care Cancer. doi:10.1007/s00520-015-2967-3.