Allogeneic BCMA-Directed CAR-T in Multiple Myeloma: Slated to Hit Phase 1 in 2019
The construct from Allogene has been engineered to avoid the serious immune-related complications linked to allogeneic transplantation.
The construct from Allogene has been engineered to avoid the serious immune-related complications linked to allogeneic transplantation.
Early results of phase 1, dose-escalation trial demonstrate efficacy and safety of P-BCMA-101 CAR-T cell therapy in patients with R/R MM.
A single-center study demonstrated that induction therapy can influence OS and DFS in patients with intermediate or high NCCN risk acute myeloid leukemia.
A retrospective and prospective study of Italian adult patients with CML investigated the potential for childbearing and outcomes in this patient population.
A worldwide survey reveals that despite similar perceptions on symptom burden of ITP, patients and physicians do not agree on the effect of fatigue on quality of life.
Two simultaneous studies demonstrate improved progression-free survival and overall survival in patients with uMCL who receive induction therapy with RB/RC followed by ASCT.
Stringent CR criteria may not predict clinical outcomes for patients with multiple myeloma.
US FDA recently approved rituximab biosimilar as monotherapy and in combination with chemotherapy.
Checkpoint-based therapies may sensitize patients to subsequent therapies.