Diabetes is associated with more advanced stage breast cancer, according to a new study by the Institute for Clinical Evaluative Sciences (ICES) and Women’s College Hospital.
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From Medical Express
Breast cancer more likely to be advanced stage disease at diagnosis in women with diabetes
the Oncology Nurse Advisor take:
A new study by the Institute for Clinical Evaluative Sciences (ICES) and Women’s College Hospital demonstrates that breast cancer in women with diabetes is more likely to be advanced stage at diagnosis.
The researchers reviewed cases of new invasive breast cancer diagnoses in women ages 20 to 105 years made between 2007 and 2012.
In the study, 6,115 of more 38,000 women (15.9%) had diabetes. These women were 14% more likely to present with stage II breast cancer, 21% more likely to present with stage III breast cancer, and 16% more likely to present with stage IV disease than to present with stage I.
Women with diabetes also had higher risk of lymph node metastases. In addition, mammography rates were lower among women with diabetes, possibly accounting for later stage disease at diagnosis.
Stage II or III breast cancer at diagnosis translates into a 15% decrease in 5-year survival at the time of diagnosis for these patients.
The researchers suggest that breast cancer screening practices may need to be modified for women with diabetes to reduce later-stage detection.
