Among patients with multiple myeloma, high compliance with exercise was associated with improvements in fatigue, according to a study published in the October 2015 issue of the journal Supportive Care in Cancer.
Because exercise is considered beneficial and safe in patients with multiple myeloma, which is commonly associated with osteolytic bone disease and anemia, resulting in skeletal fragility, persistent fatigue, pain, and reduced quality of life, researchers at the Jewish General Hospital in Montreal, Canada, sought to evaluate the extent of exercise compliance in this patient population.
For the retrospective study, researchers analyzed data from 41 patients with multiple myeloma who participated in a hospital-based rehabilitation program while undergoing chemotherapy. Results showed that exercise compliance was 71% at follow-up and was associated with a decrease in fatigue severity scores.
Researchers found that participants with a history of pathological fracture, spinal cord compression, or radiation were at an increased risk for noncompliance and may therefore require additional supervision to improve exercise compliance.
Multiple myeloma (MM) is often associated with osteolytic bone disease and anemia, resulting in skeletal fragility and persistent fatigue, pain, and reduced quality of life. Exercise is considered safe and beneficial for this population.