To the best of our knowledge, this is the first case study of Apatinib treatment for ATC. The prompt and sustained response suggests the possibility that inhibitors targeting VEGFR-2 may be a novel option to control advanced ATC, warranting clinical verifications with larger sample sizes.

Ethics Approval and Consent

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The study was under permission of the ethics committee of Shanghai Jiao Tong University Affiliated Sixth People’s Hospital. Written informed consent was received from the patient for publication including the accompanying data.


The authors thank the patient and her family members for their participation in this study.


The authors report no conflicts of interest in this work.

Lin Cheng,1 Qiong Jiao,2 Yuchen Jin,1 Hao Fu,1 Huizhen Zhang,2 Libo Chen1

1Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China; 2Department of Pathology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, People’s Republic of China
Correspondence: Libo Chen

Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, 600 Yishan Road, Shanghai 200233, People’s Republic of China
Tel +86-21-24058871
Fax +86-21-64941720
Email [email protected]


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Source: OncoTargets and Therapy.
Originally published December 2, 2019.

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