CONCLUSION

The novel nanosomal docetaxel lipid suspension (NDLS)-based chemotherapy was effective and well tolerated in managing breast cancer in all settings. Furthermore, NDLS is being evaluated prospectively in patients with triple-negative breast cancer (ClinicalTrials.gov identifier: NCT03671044)

Acknowledgments

The authors thank Mr Shreekant Sharma, MPharm, ISMPP CMPPTM (Lambda Therapeutic Research Ltd., Ahmedabad, Gujarat, India) for providing writing assistance and Dr Venugopal Madhusudhana, MBBS, EPBM, ISMPP CMPPTM (Lambda Therapeutic Research Ltd., Ahmedabad, Gujarat, India) for additional editorial assistance for the development of this manuscript. The authors also thank the clinical data management and biostatistics department of Lambda Therapeutic Research Ltd. for their contribution in the preparation of the statistical analysis report in this retrospective data collation and analysis.


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Author Contributions

SS, RP, GB, SKDM performed the research, were involved in the acquisition of data, critically revised the manuscript for important intellectual content, and approved the final manuscript. NJ, DB, MAK and IA designed the study, were involved in the data interpretation, critically revised the manuscript for important intellectual content, and approved the final manuscript. All authors made substantial contributions to this study and agree to be accountable for all aspects of the work.

Funding

This study was funded by an unrestricted research grant by Intas Pharmaceuticals Ltd., Ahmedabad, Gujarat, India.

Disclosure

Drs Mujtaba A Khan, Deepak Bunger and Nisarg Joshi are employees of Intas Pharmaceuticals Ltd., India, and the product being mentioned is manufactured and marketed by Intas Ltd. Dr Imran Ahmad is an employee of Jina Pharmaceuticals Inc., USA. The authors report no other conflicts of interest in this work.

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