SNMM is a rare disease that harbors a poor prognosis. Distant metastasis is the most common cause of treatment failure. The variability of the disease and the emergence of new treatment modalities necessitate an MDT approach for the optimal management of treatment choice, treatment side effects, and follow-up.

Surgery remains the mainstay of treatment in patients with SNMM. Adjuvant RT seems to improve local control, without a substantial effect on overall survival. Chemotherapy does not play a significant role as a primary treatment, while immunotherapy may confer survival benefit to patients with metastatic disease.

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Cindy Cohen is thanked for her editorial assistance.


The authors report no conflicts of interest in this work.


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Source: OncoTargets and Therapy.
Originally published March 16, 2020.

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