Background: Cachexia affects nearly 50–80% of cancer patients, and most studies have only focused on elderly patients. We investigated preoperative cachexia in gastric cancer (GC) patients by age group and comprehensively analyzed the impact of preoperative cachexia on the prognosis of GC patients in all age groups.Methods: In total, 575 patients were prospectively analyzed. The effect of…
[Cancer Management and Research] Researchers sought an alternative regimen for urine alkalization in patients receiving high-dose methotrexate. The typical regimen, IV sodium bicarbonate, has been on shortage. This study determined the safety of an oral regimen of sodium bicarbonate and acetazolamide to achieve a urine pH >7, which is necessary for safe administration of high-dose methotrexate.
[Cancer Management and Research] In a meta-analysis of 12 clinical studies, researchers sought to determine if patients with HER2-overexpression breast cancer experienced better OS with neoadjuvant or adjuvant trastuzumab, and to assess LRR rate in women with this tumor and treatment after mastectomy and after BCT.
[OncoTargets and Therapy] Despite the success of PD-1 blockade in the treatment of other solid tumors, only surgery at the early stage is an effective curative treatment of sarcoma. This review summarizes recent progress achieved in the use of anti-PD-1 therapy for sarcoma.
[OncoTargets and Therapy] In this patient case, after 2 misdiagnoses and surgery, a diagnosis of spinal epidural DLBCL was made and the patient was treated with 6 cycles of R-CHOPE. The authors explain when to suspect PSEL in patients with spinal cord compression.
[OncoTargets and Therapy] This systematic review and meta-analysis compared MWA and RFA in the treatment of minimally invasive liver cancer. Local tumor progression, technique efficacy, OS, DFS, intrahepatic de novo lesions, extrahepatic metastases, length of stay, and complications were analyzed.
[Breast Cancer: Targets and Therapy] A population-based case-control study explored whether the association between mammographic density as a risk factor for breast cancer differs across breast cancer tumor subtypes.
[Cancer Management and Research] This retrospective study investigated the likelihood of CVD-related chronic conditions being diagnosed in survivors of nonmetastatic CRC and of effective management of these conditions over 12 months following CRC diagnosis.
[Cancer Management and Research] Researchers analyzed data to determine the features of ultra-late recurrence of NSCLC, defined as recurrent disease more than 10 years after curative resection.
[Journal of Hepatocellular Carcinoma] Although prognosis is poor for patients with hepatocellular carcinoma (HCC), especially those with cirrhosis, a prolonged subclinical growth period offers a window of time for curative treatment. In this review, researchers discuss the current status of screening, and what can be done to improve its potential.