Atezolizumab Can Induce Response in Alveolar Soft Part Sarcoma
Anti-PD-L1 agent induces sustained responses seen in about one-third of patients with advanced alveolar soft part sarcoma.
Sarcoma
Pembrolizumab Produces Responses in Some Rare Sarcomas
Pembrolizumab yielded responses in patients with chordoma, desmoplastic small round cell tumors, epithelioid sarcoma, and other rare sarcomas.
Case Series Describes Link Between Koebner Phenomenon and Kaposi Sarcoma
Researchers described possible associations between Kaposi sarcoma and Koebner phenomenon in a case series of patients with lesions appearing after a prior cutaneous injury.
Intratumoral Microbiome in Soft Tissue Sarcoma Linked to Prognosis
Researchers explored the possibility of an intratumoral microbiome being present in soft tissue sarcoma, similar to other cancer types.
Location of KIT Mutations Impacts Response to TKIs in Patients With GIST
The location of KIT mutations is associated with response to ripretinib and sunitinib in patients with previously treated GIST, research suggests.
Tecentriq Approved for Unresectable or Metastatic Alveolar Soft Part Sarcoma
The approval was based on data from a phase 2 study that included 49 patients with unresectable or metastatic ASPS.
Shorter Regimen of Radiotherapy Safe for Soft Tissue Sarcoma
Findings with preoperative radiotherapy administered to dose of 42.75 Gy in 15 fractions for three weeks.
Trabectedin Improves PFS in Advanced Leiomyosarcoma
Adding trabectedin to doxorubicin doubled the median progression-free survival.
Carboplatin Deemed Acceptable Replacement for Actinomycin-D in Ewing Sarcoma
There was no significant difference in overall survival between patients who received actinomycin-D and those who received carboplatin.
High-Dose Ifosfamide Bests Topotecan-Cyclophosphamide in Relapsed/Refractory Ewing Sarcoma
Ifosfamide improved event-free and overall survival.
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