Melanoma

Melanoma News & Features

Squamous cell skin cancer involves changes to skin cells in the middle layer of the epidermis and usually presents as a growing bump with a rough, scaly surface and flat reddish patches. This type of cancer spreads faster than basal cell carcinoma, but is still relatively slow growing. About 95% of squamous cell tumors can be cured if removed promptly.

American Indians, Alaskan Natives Engage in Few Skin Cancer Prevention Behaviors

September 30, 2022

Researchers at Brigham and Women’s Hospital investigated the skin cancer prevention behaviors of these rarely studied ethnic groups.

FDA: Cases of Breast Implant-Related SCC, Various Lymphomas Reported

Brian Park, PharmD

September 26, 2022

Following an initial extensive review, the Agency identified less than 20 cases of SCC and less than 30 cases of various lymphomas in the capsule around the breast implant.

More than half of patients with resected stage 3 melanoma with BRAF V600E or V600K mutations receiving a year’s worth of adjuvant dabrafenib and trametinib were still alive 5 years later.

Prognosis Improved After Moderate ICI-Related Colitis Due to Melanoma Treatment

Jennifer Larson

September 22, 2022

Researchers explored the effects of developing ICI-related colitis on patients treated with ipilimumab as monotherapy and dual therapy for advanced melanoma.

An elderly patient speaks with a doctor.

Incidence of Cutaneous T-Cell Lymphoma Up in the U.S.

September 16, 2022

Overall incidence rate six times higher for patients aged 40 years or older versus younger than 40 years, but increase in CTCL rate significantly higher for those younger than 40 years.

First-Line Immune Checkpoint Inhibitors Underused in Metastatic Melanoma

Leah Lawrence

September 14, 2022

First-line immune checkpoint inhibitors have improved survival in patients with metastatic melanoma but remain underused in this population.

Melanoma Clinical Trials

Clinical Trial: Study of Tumor Tissue Samples From Patients With Stage I, Stage II, or Stage III Malignant Melanoma

Clinical Trial: Evaluating the Safety and the Biological Effects of Intratumoral Interferon Gamma and a Peptide-Based Vaccine in Patients With Melanoma (Mel 51)

Melanoma

American Indians, Alaskan Natives Engage in Few Skin Cancer Prevention Behaviors

FDA: Cases of Breast Implant-Related SCC, Various Lymphomas Reported

Prognosis Improved After Moderate ICI-Related Colitis Due to Melanoma Treatment

Incidence of Cutaneous T-Cell Lymphoma Up in the U.S.

First-Line Immune Checkpoint Inhibitors Underused in Metastatic Melanoma

Melanoma Clinical Trials

Clinical Trial: Study of Tumor Tissue Samples From Patients With Stage I, Stage II, or Stage III Malignant Melanoma

Clinical Trial: Evaluating the Safety and the Biological Effects of Intratumoral Interferon Gamma and a Peptide-Based Vaccine in Patients With Melanoma (Mel 51)

Clinical Trial: Study of Families With Melanoma

Clinical Trial: Individualized Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery

Clinical Trial: Combination Therapy of Topical Imiquimod Plus Multipeptide Vaccination for Cutaneous Metastases of Melanoma

Melanoma Fact Sheets

How to Prevent Skin Cancer (Fact Sheet)

Metastatic Cancer (Fact Sheet)

Risk Factors and Screening for Melanoma

Melanoma: Causes and Prevention

Staying Safe in the Sun

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First-Line Immune Checkpoint Inhibitors Underused in Metastatic Melanoma