Liver Cancer

Bavencio Plus Inlyta Approved as First-Line Tx for Advanced Renal Cell Carcinoma

By

Diana Ernst, RPh

Publish Date May 15, 2019

The Food and Drug Administration has approved Bavencio (avelumab; EMD Serono), a programmed death-ligand 1 (PD-L1) blocking antibody, in combination with Inlyta (axitinib; Pfizer), a kinase inhibitor, for the first-line treatment of patients with advanced renal cell carcinoma (RCC).

Cyramza Approved to Treat Hepatocellular Carcinoma

By

Diana Ernst, RPh

Publish Date May 13, 2019

The FDA has approved Cyramza (ramucirumab; Lilly) for use as a single agent in the treatment of patients with hepatocellular carcinoma (HCC) who have an alpha fetoprotein (AFP) of ≥400ng/mL and have been treated with sorafenib.

Higher Intake of Whole Grains May Lower Risk for Liver Cancer

Publish Date March 6, 2019

Whole grains and possibly cereal fiber, bran appear linked to lower risk for hepatocellular carcinoma.

Radiofrequency Ablation of Hepatocellular Carcinoma: A Meta-analysis of Overall Survival and Recurrence-free Survival

By

Andrea Casadei Gardini, Giorgia Marisi, Matteo Canale, et al.

Publish Date November 23, 2018

[OncoTargets and Therapy] This meta-analysis evaluates prognostic factors of OS and RFS in patients treated with radiofrequency ablation.

NHS, HPFS Show Regular Aspirin Use Reduced Hepatocellular Carcinoma Risk

By

Tiffany Garbutt, PhD

Publish Date October 17, 2018

An analysis of results from the NHS and the HPFS showed that regular use of aspirin — standard-dose 325-mg tablets — reduced hepacellular carcinoma in a dose-dependent manner.

Liver Cancer Clinical Trials

NSCLC: Study Assesses Adjuvant Chemo Decision-making Role Preferences

Clinical Trial: Bevacizumab and Erlotinib or Sorafenib as First-Line Therapy in Treating Patients With Advanced Liver Cancer

Clinical Trials: Chemoembolization Versus Radioembolization in Treating Patients With Liver Cancer That Cannot Be Treated With Radiofrequency Ablation Or Surgery

Clinical Trial: Transarterial Chemoembolization With Doxorubicin With or Without Everolimus in Treating Patients With Liver Cancer

Clinical Trial: Fusion Guided Thermal Ablation Combined With External Beam Radiation for Hepatic Neoplasms.