Chronic Myeloid Leukemia‎

Review of the Cardiovascular Risks of TKI Therapy for Chronic Myeloid Leukemia

By

Jennifer Larson

Publish Date September 15, 2021

Tyrosine kinase inhibitors have improved survival outcomes for patients with CML, but these agents also have a greater risk for adverse cardiovascular events.

Pulmonary Hypertension Risk Increases With Tyrosine Kinase Inhibitor Use

By

Jessica Nye, PhD

Publish Date September 2, 2021

A review of data from patients with CML treated with TKIs identified risk factors for developing pulmonary hypertension in these patients.

Researchers Seek to Assess Monthly Adherence to Oral Chemotherapy Agents in Chronic Myeloid Leukemia

By

Jessica Nye, PhD

Publish Date August 16, 2021

Researchers seek to characterize adherence trajectories, determine how side effects or financial status influence adherence, assess how adherence effects clinical outcomes, and explore unique patient perspectives.

New-Generation BCR-ABL TKIs Linked to Increased Risk of Hepatotoxicity in Patients With Chronic Myeloid Leukemia

By

Jennifer Larson

Publish Date August 4, 2021

Researchers sought to determine the risk of hepatotoxicity for patients with CML treated with 4 newer TKIs compared with imitanib.

Therapeutic Drug Monitoring Improved Incidence of Pleural Effusion With Dasatinib for CP-CML

By

Vicki Moore, PhD

Publish Date July 12, 2021

A dose-reduction strategy in patients with CP-CML receiving dasatinib was shown to be feasible and may reduce adverse effects in these patients.

Leukemia Clinical Trials

Clinical Trial: Molecular Epidemiology of Childhood Leukemia (Aka The California Childhood Leukemia Study) (CCLS)

Clinical trial focusing on the molecular epidemiology of childhood leukemia. Molecular Epidemiology of Childhood Leukemia (Aka The California Childhood Leukemia Study) (CCLS)

Clinical Trial: Genetic Study of Chronic Lymphocytic Leukemia Families

Clinical trial focusing on genetics and chronic lymphocytic leukemia. Genetic Study of Chronic Lymphocytic Leukemia Families

Clinical Trial: Banking of Chronic Lymphocytic Leukemia Tumor Cells for Vaccine Generation

Clinical trial focusing on vaccine generation from chronic lymphocytic leukemia tumor cells. Banking of Chronic Lymphocytic Leukemia Tumor Cells for Vaccine Generation

Clinical Trial: Phase I Study of GNKG168 in Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia

Clinical trial focusing on GNKG168. Phase I Study of GNKG168 in Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia

Clinical Trial: Study of Carfilzomib in Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic Leukemia (PLL)

Clinical trial focusing on carfilzomib Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic Leukemia (PLL). Study of Carfilzomib in Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic Leukemia (PLL) .