Leukemia

Sorafenib Maintenance Therapy After Allo-HSCT Improves Outcomes in FLT3-ITD–Positive AML

By

Lauren Dembeck, PhD

Publish Date August 4, 2020

Among patients with FLT3-internal tandem repeats, sorafenib maintenance therapy reduces the risk of relapse and death after allo-HSCT.

Allogeneic-HSCT Outcomes With Varied Donor Sources in Adult T-Cell Leukemia/Lymphoma

By

Vicki Moore, PhD

Publish Date August 3, 2020

Researchers studied the pros and cons of transplantation from different donor sources to enhance overall outcomes of allo-HSCT in adults with T-cell malignancies.

Identifying Risk Factors for Invasive Fungal Infection in Ibrutinib-Treated CLL Patients

By

Susan Moench, PhD, PA-C

Publish Date July 30, 2020

Ibrutinib-mediated macrophage inhibition may underlie an increased risk of invasive fungal infection in patients with CLL treated with this agent.

Genetic Prognostic Factors in CLL Treated With Novel Compounds

By

Andrea S. Blevins Primeau, PhD, MBA

Publish Date July 29, 2020

Obinutuzumab plus venetoclax was associated with improved outcomes compared with obinutuzumab plus chlorambucil, regardless of the presence of unfavorable genetic prognostic factors.

Dental Screenings Prior to Induction Chemotherapy for Acute Myeloid Leukemia

By

Vicki Moore, PhD

Publish Date July 23, 2020

Researchers found that identifying and treating acute odontogenic disease before induction chemotherapy prevented infectious dental emergencies in AML patients.

Leukemia Clinical Trials

Clinical Trial: Molecular Epidemiology of Childhood Leukemia (Aka The California Childhood Leukemia Study) (CCLS)

Clinical trial focusing on the molecular epidemiology of childhood leukemia. Molecular Epidemiology of Childhood Leukemia (Aka The California Childhood Leukemia Study) (CCLS)

Clinical Trial: Genetic Study of Chronic Lymphocytic Leukemia Families

Clinical trial focusing on genetics and chronic lymphocytic leukemia. Genetic Study of Chronic Lymphocytic Leukemia Families

Clinical Trial: Banking of Chronic Lymphocytic Leukemia Tumor Cells for Vaccine Generation

Clinical trial focusing on vaccine generation from chronic lymphocytic leukemia tumor cells. Banking of Chronic Lymphocytic Leukemia Tumor Cells for Vaccine Generation

Clinical Trial: Phase I Study of GNKG168 in Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia

Clinical trial focusing on GNKG168. Phase I Study of GNKG168 in Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia

Clinical Trial: Study of Carfilzomib in Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic Leukemia (PLL)

Clinical trial focusing on carfilzomib Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic Leukemia (PLL). Study of Carfilzomib in Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic Leukemia (PLL) .