Hematologic Cancers

No Link Found Between Hepatitis C Infection and Extrahepatic Cancers

By

Leah Lawrence

Publish Date January 23, 2020

A study of an Asian population failed to find a link between the virus and malignancies outside of the liver.

Ruxolitinib Plus PEG-IFNα2 for Patients With Polycythemia Vera or Myelofibrosis

By

Vicki Moore, PhD

Publish Date January 21, 2020

The study’s primary endpoint was efficacy, determined by complete remission, peripheral blood cell count remission, quality of life, and JAK2 V617F allele burden.

Avatrombopag Designated Orphan Drug for Chemo-Induced Thrombocytopenia

By

Steve Duffy

Publish Date January 21, 2020

The FDA has granted Orphan Drug designation to avatrombopag for the potential treatment of chemotherapy-induced thrombocytopenia, a complication that may lead to chemotherapy dose delays and regimen changes.

Asciminib Shows Clinical Activity for Pretreated CML in Phase 1 Trial

By

Christina Bennett, MS

Publish Date January 16, 2020

Asciminib appeared to have clinical activity in a population of heavily pretreated patients with chronic myeloid leukemia, including those with a T315I mutation.

MRD Status Assessed by Flow Cytometry Predicts Treatment Efficacy in Newly Diagnosed Multiple Myeloma

By

Susan Moench, PhD, PA-C

Publish Date January 15, 2020

Next-generation flow cytometry involves assessments of both plasma cell-surface antigens and immunoglobulin light-chain expression.