Head and Neck Cancer

Factors Identified for Poor Long-Term Survival in RT-Treated Patients With Oropharyngeal Cancer

By

Susan Moench, PhD, PA-C

Publish Date January 6, 2021

This analysis identified the factors for poor long-term survival in radiotherapy (RT)-treated patients with oropharyngeal cancer (OPC).

Gavreto Gets Accelerated Approval for RET-Altered Thyroid Cancers

By

Brian Park, PharmD

Publish Date December 8, 2020

The approval was based on data from the phase 1/2 ARROW trial which evaluated the efficacy and safety of Gavreto in patients with RET-mutant MTC.

Statistical Index Suggests That Many ICI Trials Show Uncertain Clinical Benefit

By

Andrea S. Blevins Primeau, PhD, MBA

Publish Date November 9, 2020

The survival-inferred fragility index of phase 3 trials for immune checkpoint inhibitors suggests that, despite statistical significance, survival data do not show a robust clinical benefit.

Experts Establish Surgical Priority Ranking for Head and Neck Cancers

By

Leah Lawrence

Publish Date September 15, 2020

Experts have developed a new tool for surgical prioritization and ranking for patients with head and neck cancer in a scarce-resource settings associated with the COVID-19 pandemic.

RET Inhibitor Demonstrates Efficacy in RET-Altered Thyroid Cancer

By

Andrea S. Blevins Primeau, PhD, MBA

Publish Date September 7, 2020

Treatment of RET-altered thyroid cancer with selpercatinib, a RET inhibitor, resulted in durable efficacy with a tolerable safety profile in a phase 1/2 trial.

Transoral Robotic Surgery Ups Survival in Oropharyngeal Cancer

Publish Date August 25, 2020

Outcomes and survival improved for early-stage oropharyngeal cancer, but not other cancers.

Weight and Swallowing-Related Quality of Life in Patients Treated for Oropharyngeal Cancer

By

Vicki Moore, PhD

Publish Date August 20, 2020

Single-center study reports on the effects of oropharyngeal cancer treatment at 3, 6, and 12 months after chemoradiotherapy or radiotherapy alone, and with and without a feeding tube.

Adding Radiotherapy to Chemotherapy Boosts Survival in Nasopharyngeal Carcinoma

By

Christina Bennett, MS

Publish Date August 7, 2020

Patients treated with chemotherapy plus radiotherapy had a 64% reduced likelihood of disease progression or death compared with those who underwent chemotherapy alone.

A 6-Gene Expression Signature May Predict Benefit From Induction Chemotherapy in Locally Advanced Nasopharyngeal Cancer

By

Susan Moench, PhD, PA-C

Publish Date August 7, 2020

The purpose of this study was to develop and test a gene-expression profiling assay to facilitate patient selection for induction chemotherapy in the setting of LA-NPC.

Increasing Trends in Thyroid Cancer Burden Since 1990 Observed Worldwide

By

Rose Reeb

Publish Date July 21, 2020

Increasing trends in global thyroid cancer burden were observed in a cross-sectional study using data from 195 countries in 21 regions.