Although RPLS induced by a targeted drug, such as bevacizumab, is rare, given the gradual popularization of targeted drugs and gradual recognition of RPLS, the incidence of RPLS may increase in the future. RPLS can be classified as an acute complication associated with cancer treatment, and the diagnosis and treatment of RPLS can be standardized. A diagnosis can be obtained through clinical presentation and typical MRI images. The principle of treatment involves stopping the drug immediately and providing aggressive treatment for normotension. The prognosis of the vast majority of cases is good. There are few reports on whether RPLS will relapse if the patient continues to take the medicine. In this case, the patient continued to take apatinib at half the dose 1 week later. She did not experience RPLS again. The cause was unknown. Perhaps it was an open question.

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Source: OncoTargets and Therapy.
Originally published July 30, 2018.