According to a new study published in the journal Nature, a team of researchers has found that gut bacteria associated with high fat diets cause an increased risk of bowel cancer. In the study, researchers fed some mice with a predisposition to bowel cancer a high fat diets and fed other mice a normal fat diet.
Then, the researchers took fecal samples of the mice to observe the differences in gut bacteria between the two groups of mice. Over time, they found that the mice fed a high fat diet had more of certain bacteria and less of others. The researchers noted that the change in gut bacteria lowered immunity defenses against bowel cancers and therefore was linked to an increase in the development of bowel cancer.
Furthermore, when the researchers killed off all of the bacteria in some mice, they observed a decrease in the incidence of bowel cancers. In addition, when they transferred gut bacteria from mice with bowel cancers to mice without, those mice had an increased risk of developing bowel cancers compared with those that did not receive the bacteria transfer.
The researchers suggest that a high fat diet should be avoided or modified to decrease the risk of developing bowel cancer.
A large team of researchers, with members primarily from Germany, has found evidence that implicates high fat diets as a cause of bowel cancer due to a link with gut bacteria. In their paper published in the journal Nature, the team describes the results of research they conducted using mice that have a gene associated with the onset of bowel cancer.
Medical scientist have known for some time that there is a link between high fat diets and various cancers of the bowels, but until now were not able to explain why such a connection exists. Some have suggested that it’s tied to obesity, or other side-effects that occur when a person eats a diet high in fat. In this new effort, the researchers have found evidence that exonerates obesity and instead implicates gut bacteria.