Regular aspirin use is associated with a lower risk of breast cancer among women with diabetes, a study published in the Journal of Women’s Health has shown.
For the study, researchers at Chung Shan Medical University Hospital and Hung Kuang University, Taichung, Taiwan, analyzed data on 148,739 patients with diabetes, mean age 63.3 years; 27,378 of the women were taking aspirin.
The researchers found that the use of aspirin in patients with diabetes reduced the risk of breast cancer by 18%, after adjusting for potential confounders, age, and other comorbidities.
The study findings are based on retrospective data retrieved from the National Health Insurance Research Database in Taiwan from January 1, 1998, to December 31, 2011. The investigators compared women with diabetes taking low-dose aspirin regularly (75 to 165 mg daily) to women with diabetes not regularly taking low-dose aspirin.
The researchers reported that a high cumulative dose of aspirin over the 14-year study period reduced breast cancer risk by 47%, whereas low and medium cumulative doses did not reduce risk.
1. Yang YS, Kornelius E, Chiou JY, et al. Low-dose aspirin reduces breast cancer risk in women with diabetes: a nationwide retrospective cohort study in Taiwan [published May 24, 2017].
J Womens Health. doi: 10.1089/jwh.2016.6040