Brain Cancer

Assay-Guided Therapy Improves Survival in High-Grade Glioma

By

Leah Lawrence

Publish Date April 19, 2022

Patients who received treatment selected by the ChemoID assay had superior progression-free survival and overall survival.

Risk of Leptomeningeal Metastasis in Melanoma Linked to Anatomic, Surgical Factors

By

Sucharita Mistry, PhD

Publish Date February 11, 2022

Researchers found that entry into the ventricle space during surgical resection elevated the risk of leptomeningeal disease in patients with melanoma brain metastases.

No Benefit Seen With Armodafinil for Fatigue in Patients With High-Grade Glioma

By

Vicki Moore, PhD

Publish Date January 14, 2022

Treatment of fatigue related to high-grade glioma using armodafinil did not show a meaningful benefit over placebo in a phase 3 trial.

2008 to 2017 Saw Drop in Malignant Brain Tumor Incidence

Publish Date August 31, 2021

Incidence among children, adolescents increased 0.5 to 0.7 percent; malignant tumor incidence highest for males, non-Hispanic Whites

Sodium Thiosulfate Appears to Decrease Ototoxic Effects of Platinum Chemo Without Compromising Efficacy

By

Leah Lawrence

Publish Date August 12, 2021

More studies are needed to confirm if there is an effect on survival, according to researchers.

Brain Cancer Clinical Trials

Underuse of Standard Care in Early NSCLC May Impact Adjuvant Trial Results

The lack of guideline-concordant care for early-stage non-small cell lung cancer may affect the interpretation of adjuvant trial results, according to researchers.

Financial Reimbursement Program a Feasible Way to Diversify Clinical Trial Populations

Researchers sought to determine if offering financial reimbursement with or without a follow-up phone call would improve the diversity of patients participating in clinical trials.

Study Time Frame, Expectations of Participants Significant to Older Adults With Cancer and Their Caregivers

A qualitative descriptive study identified the interest and willingness to participate in clinical trials of patients 65 and older and their caregivers.

Reasons for Cancer Clinical Trial Withdrawal Often Not Understood

A structured interview study sought to understand patient experiences after being withdrawn from a cancer clinical trial.

Model More Accurately Predicts Outcomes of Radiotherapy in Cancer Patients

The genomic-adjusted radiation dose (GARD) model predicts outcomes of radiotherapy.