Brain Cancer

Novel Therapy for Diffuse Intrinsic Pontine Glioma Fast Tracked

By

Diana Ernst, RPh

Publish Date March 4, 2021

Oblato plans to evaluate OKN-007 for diffuse intrinsic pontine glioma in a phase 1/2 trial this year.

American Cancer Society 2021 Statistics Report Shows Continuous Decline in Cancer Mortality Rate, Illuminates Disease-Specific Trends

By

Rachel Narozniak, MA

Publish Date February 4, 2021

The American Cancer Society’s annual report approximates the new cancer diagnoses and deaths expected in 2021 and identifies impactful patterns in oncology care.

Immunotherapy Improves Survival Despite Brain Metastases

By

Jody A. Charnow

Publish Date September 17, 2020

Immunotherapy improved median overall survival by 7.5 months regardless of what other treatments patients received.

FDA Grants Orphan Drug Status to Berubicin for Malignant Gliomas

By

Brian Park, PharmD

Publish Date June 16, 2020

he designation is supported by data from a phase 1 trial conducted by Reata Pharmaceuticals in 2016. Findings from the study showed 44% of patients treated with berubicin (n=11 out of 25) experienced a statistically significant improvement in progression free survival.

Short Treatment Delays May Not Hamper Survival in Glioblastoma

By

Christina Bennett, MS

Publish Date May 12, 2020

For patients with glioblastoma, short delays in the initiation of chemoradiotherapy after surgery were not linked to worse survival — yet initiation too soon was.

Brain Cancer Clinical Trials

Underrepresentation of Women in Clinical Trials Persists

Clinical trials leading to US FDA approvals of anticancer therapies continue to underrepresent women.

Brain Cancer Treatment Regimens

View detailed drug regimens for the treatment of brain cancer, including treatments such as temozolomide, carboplatin, and methotrexate.

Ipilimumab and Nivolumab as First-Line Treatment of Patients with Renal Cell Carcinoma: The Evidence to Date

[Cancer Management and Research] A review of past and ongoing trials using ipilimumab-nivolumab combination therapy for metastatic renal cell carcinoma.

Call for ‘Challenge Trials’ to Hasten COVID-19 Vaccine Development

Scientists say such ‘human challenge trials’ are of ‘vast importance’ in speeding up the testing of vaccines.

African-American Participation Inadequate in Cancer Drug Trials

Consistent underrepresentation seen in clinical trials evaluating medications across major cancer types.