Researchers at St Jude Children’s Research Hospital sought to determine what indicators in survivors of CNS tumors can predict the survivor’s ability to live independently as an adult.
[OncoTargets and Therapy] Management of brain metastases in patients with EGFR-mutant NSCLC is controversial. In this study, researchers find combination and sequential treatment with EGFR-TKIs, chemotherapy, and radiotherapy is beneficial.
In this phase 2 study, researchers randomly assigned 79 patients with immunotherapy-naive melanoma with brain metastases to receive either nivolumab plus ipilimumab or nivolumab alone.
[OncoTargets and Therapy] A meta-analysis was conducted to evaluate the effect of abnormal EGFR expression on overall survival (OS) in patients with glioma.
Researchers argue that palliative care integration into treatment regimens contribute to improving the quality of life for patients in phase 1 clinical trials.
FORTIS, a phase 3 randomized study, evaluated the effects of dose intensity of the frontline fludarabine/cyclophosphamide/rituximab on progression-free and overall survival in adult patients with CLL.
Using a cohort of women from the POSH Study, researchers sought to determine risk factors for changes in weight among younger, premenopausal women receiving adjuvant chemotherapy for early-stage breast cancer.
Researchers conducted a meta-analysis to determine the incidence of adverse events among patients assigned to placebo-receiving groups in randomized clinical trials.
