Hematopoietic Cell Transplantation

Metronidazole, Vancomycin Recommended for <i>C Difficile</i> in Pediatric Oncology, HSCT

Metronidazole, Vancomycin Recommended for C Difficile in Pediatric Oncology, HSCT

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An international multidisciplinary panel of experts in pediatric oncology and infectious diseases convened to develop recommendations for the prevention and treatment of C difficile infection in pediatric patients with cancer or who are undergoing HSCT.

Myeloablative Conditioning Effective in AML Secondary to MDS/MPN Prior to Allogeneic HCT

Myeloablative Conditioning Effective in AML Secondary to MDS/MPN Prior to Allogeneic HCT

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In the EBMT ALWP study, researchers sought to determine the efficacy of myeloablative conditioning to reduce the risk for post allogeneic HCT in patients with sAML without significantly increasing non-relapse mortality.

Pre-HSCT Conditioning May Improve Physical Functioning in Hematologic Cancers

Pre-HSCT Conditioning May Improve Physical Functioning in Hematologic Cancers

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In this retrospective study, researchers assessed the outcomes of 88 patients with hematologic disease who underwent HSCT.

Nonmyeloablative/Reduced-Intensity Conditioning May Reduce Mucositis in HCT

Nonmyeloablative/Reduced-Intensity Conditioning May Reduce Mucositis in HCT

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Researchers sought to determine if NMA or reduced-intensity conditioning with busulfan improved severity/duration of oral mucositis compared with myeloablative conditioning in patients with hematologic cancer undergoing HCT.

Long-Term Azithromycin May Increase Risk of Relapse of Blood Cancers After HSCT

Long-Term Azithromycin May Increase Risk of Relapse of Blood Cancers After HSCT

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US FDA issues a recommendation on use of azithromycin in patients with hematologic malignancies who have undergone HSCT.

Effect of HSCT on HRQOL and Posttraumatic Stress in Young Adult Cancer Survivors

Effect of HSCT on HRQOL and Posttraumatic Stress in Young Adult Cancer Survivors

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Study sought to determine the health-related QOL and posttraumatic stress symptoms in adolescent and young adult cancer survivors post-HSCT compared with their healthy peers.

Qualitative Analysis of Myeloma Patients' Experience Following Hematopoietic Stem Cell Transplant

Qualitative Analysis of Myeloma Patients' Experience Following Hematopoietic Stem Cell Transplant

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In this study, researchers investigated the effects of exercise on physical and psychological recovery after autoHSCT for multiple myeloma.

Low Level Laser Therapy May Prevent Oral Mucositis During HSCT Conditioning

Low Level Laser Therapy May Prevent Oral Mucositis During HSCT Conditioning

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Researchers assessed the effectiveness of low level laser therapy in preventing or minimizing oral mucositis in patients with hematologic cancers preparing to undergo HSCT. Results were presented at the 2018 ONS Annual Congress.

Taste Changes After Hematopoietic Stem Cell Transplant Affect QOL in Blood Cancers

Taste Changes After Hematopoietic Stem Cell Transplant Affect QOL in Blood Cancers

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Slight changes in taste perceptions are noted in patients undergoing HSCT for hematologic cancers. In this study, researchers sought to determine how these changes affect quality of life and nutritional intake.

Defibrotide an Effective Option for SOS/VOD in Patients Undergoing HSCT

Defibrotide an Effective Option for SOS/VOD in Patients Undergoing HSCT

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Sinusoidal obstruction syndrome (or hepatic veno-occlusive disease), a complication observed in patients who undergo HSCT, is managed with defibrotide. In this study, investigators assessed its efficacy and patient response to therapy.

Stem Cell Transplant Patients Benefit From Inpatient Palliative Care

Stem Cell Transplant Patients Benefit From Inpatient Palliative Care

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Palliative care added to transplant care improved relief from depression and PTSD symptoms following hematopoietic stem cell transplantation.

Blood-Forming Stem Cell Transplants (Fact Sheet)

Blood-Forming Stem Cell Transplants (Fact Sheet)

This fact sheet reviews bone marrow transplantation (BMT) and peripheral blood stem cell transplantation (PBSCT) as they relate to the cancer treatment.

Inpatient Palliative Care Improves QoL for Patients Hospitalized for HCT

Inpatient Palliative Care Improves QoL for Patients Hospitalized for HCT

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Palliative care improved quality of life, depression, anxiety, and symptom burden in patients with hematologic malignancies hospitalized for hematopoietic stem cell transplantation (HCT).

Double Autologous HCT Improves Outcomes in High-risk Pediatric Neuroblastoma

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Adding a second autologous hematopoietic cell transplantation (HCT) to standard therapy improves outcomes for pediatric patients with high-risk neuroblastoma.

Dose of Transplanted Blood-Forming Bone Marrow Cells Affects How Transplanted Cells Act

Dose of Transplanted Blood-Forming Bone Marrow Cells Affects How Transplanted Cells Act

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Bone marrow transplantation can be improved by optimizing the dose of transplanted hematopoietic stem cells, according to recent results from a mouse model.

Frailty Is a Concerning Factor Among Young Bone Marrow Transplant Survivors

Frailty Is a Concerning Factor Among Young Bone Marrow Transplant Survivors

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Incidence of frailty among young survivors of bone marrow transplant is similar to that of the elderly population, and increases the risk of death compared with nonfrail survivors.

HCT-related Concerns at Discharge Associated With Depression

HCT-related Concerns at Discharge Associated With Depression

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Hematopoietic cell transplantation (HCT)-related concerns at the time of hospital discharge predict increases in depression but not in anxiety.

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