Study Finds Increased Risk of MGUS in Vietnam Vets Exposed to Agent Orange
the ONA take:
Vietnam War veterans exposed to Agent Orange, an herbicidal agent used for warfare, have more than a 2-fold increased risk for monoclonal gammopathy of undetermined significance (MGUS), according to a new study published online ahead of print in JAMA Oncology.
MGUS is a precursor to multiple myeloma. Patients with MGUS have lower antibody levels, plasma cells in the bone marrow, and no symptoms. Therefore, no treatment is indicated for patients with MGUS, but patients should be followed up every 6 months to determine if MGUS has transformed into multiple myeloma or a similar lymphoproliferative disorder.
For the study, a team of researchers led by Ola Landgren, MD, PhD, of Memorial Sloan Kettering Cancer Center in New York analyzed samples from 958 male veterans of the Vietnam War. Half of those were Operation Ranch Hand veterans who participated in aerial Agent Orange spray missions.
"Our findings of increased MGUS risk among Ranch Hand veterans support an association between Agent Orange exposure and multiple myeloma," the study concludes.
Agent Orange was widely used during the Vietnam War.
Sign Up for Free e-newsletters
- Is Radioimmunotherapy a Path Forward for Melanoma?
- FDA Approves Mogamulizumab-kpkc for Rare Subtypes of Non-Hodgkin Lymphoma
- New PDL1 Inhibitors for Non-small Cell Lung Cancer: Focus on Pembrolizumab
- Intensive Chemotherapy May Not Be Effective in MDS or AML After MDS
- ASCO Endorses SIO Guideline for Integrative Therapies in Breast Cancer
- NCCIH HerbList App Launched to Provide Information on Herbal Products
- Metformin Use May Improve Survival Outcomes in Bladder Cancer
- Higher Vitamin D Levels Associated With Lower Breast Cancer Risk
- Nurse-Led Program Improves Health, Financial Outcomes in Outpatient Chemotherapy
- Seeking Reliable Information on Herbal Products
- Disparities Remain in Prevalence of Cancer Screening Tests
- Hope, Gratitude, and Spirituality: What They Mean to Cancer Patients
- FDA, EU Approvals Sought for Split Dose Regimen of Daratumumab for Multiple Myeloma
- 8 Hours of Bedrest May Be Ideal After Intrathecal Chemotherapy in Hematologic Cancers
- Combined Digital Screening Best for Detecting Breast Cancers
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|