Research group looking to bring Cuba's lung cancer vaccine to the United States
the ONA take:
As relations between the United States and Cuba normalize, groundbreaking lung cancer research and a vaccine may be early imports from the island nation.
A group that included from Roswell Park Cancer Institute’s (RPCI) president and CEO and New York Governor Andrew Cuomo met in face-to-face meetings with representatives and researchers from Cuba’s Center for Molecular Immunology (CIM) in which they finalized an agreement to bring CimaVax, the CIM’s lung cancer vaccine, to the United States.
CimaVax targets a growth factor (EGF) necessary for lung cancer to survive. By depleting the growth factor, the vaccine starves the cancer and slows its progression, prolonging patients’ lives.
Expansive clinical trials with published data show the vaccine effectively prolonged life, especially among patients younger than 60 years, compared with standard care, with minimal vaccine-related toxicity. The vaccine is administered as an injection in the shoulder once per month.
RPCI is preparing the paperwork for the FDA, and is hoping the FDA can begin its inspection within the next 2 to 3 months.
In addition, extensive safety data is currently available and may enable investigators to skip straight to a phase II study in patients. The researchers estimate the clinical trials, FDA approval, and other regulatory requirements would take 5 years to complete.
CimaVax is the first of several other potential collaborations between RPCI and CIM. Additional collaborations include potential use of CimaVax on colon, head and neck, prostate, breast, and pancreatic cancers, and a second vaccine that targets blood cancers.
As relations between the United States and Cuba normalize, groundbreaking lung cancer research and a vaccine may be early imports.
Sign Up for Free e-newsletters
- Hodgkin Lymphoma Survivorship Marked by Periods of Actionable Distress
- Medication, Vaccination Uptake Improved by Involving Pharmacists in Elder Cancer Care
- Dose-Escalation Mitigates Risk of Grade 3/4 Adverse Events With Ruxolitinib for Myelofibrosis
- Stem Cell Transplantation Superior to Chemotherapy for Relapsed/Refractory DLBCL, Follicular Lymphoma
- Study Reveals Relationship of Sleep Duration, Diabetes Risk in Cancer Survivors
- Navigating Prostate Cancer: A Patient's Experience From Diagnosis to Survivor
- Cell Phones and Cancer Risk (Fact Sheet)
- How Likely Are Oncologists to Refer for Palliative Care? Depends on Their Age
- Use of Corticosteroids With PD-1 or PD-L1 Inhibitors Associated With Poorer Outcomes in NSCLC
- Chemoimmunotherapy Increases Survival in Triple-Negative Breast Cancer
- Risk for Colon Cancer, Osteogenic Sarcoma Higher With Presence of Diamond-Blackfan Anemia
- G-CSF Support Increases Overall Survival, But Risk of Secondary Malignancies Also Higher
- Report From Childhood Cancer Survivor Study Identifies Long-Term Risks for VTE
- The Effect of Intravenous Hydration Strategy on Plasma Methotrexate Clearance During Intravenous High-dose Methotrexate Administration in Pediatric Oncology Patients
- Outcomes Worse for Minimally Invasive Hysterectomy vs Open Surgery
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
|Head and Neck Cancer||Regimens||Drugs|