Cancer diagnoses diminishes adherence to diabetes medications

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According to a new study published in the journal Diabetologia, patients with diabetes become less adherent to their antihyperglycemic medications after receiving a cancer diagnosis.

For the study, researchers sought to evaluate changes in adherence to antihyperglycemic medications used to treat diabetes after a diagnosis of cancer. Researchers identified 52,228 antihyperglycemic mediation users from the Eindhoven Cancer Registry-PHARMO Database Network in the Netherlands between 1998 and 2011. Of those, they identified 3,281 cases with cancer and 12,891 controls without cancer.

Results showed that before a cancer diagnosis, the medication possession ratio (MPR), an indicator for medication adherence, was increased by 0.10% per month. At the time of cancer diagnosis, researchers found that the MPR decreased by 6.3%, which continued to decline by 0.20% monthly thereafter.

Patients diagnosed with stage 4 cancer and those with gastroinestinal or pulmonary cancers had the largest declines in MPR. The initial 6% MPR decrease translates to a patient missing 2 days of their antihyperglycemic medications.

The findings suggest that a cancer diagnosis can diminish adherence to medications of patients' other chronic conditions.

Diabetes at midlife influences risk of diabetes and cognitive decline in later years
Patients with diabetes become less adherent to their antihyperglycemic medications after receiving a cancer diagnosis.
Diabetes patients become less adherent to their diabetes medications following a diagnosis of cancer, concludes a new study published in Diabetologia. The research is led by Marjolein Zanders, Netherlands Comprehensive Cancer Organisation, Eindhoven, the Netherlands, Jeffrey Johnson, School of Public Health, University of Alberta, Edmonton, Canada and colleagues.
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