Treatment-induced hearing loss associated with outcomes in childhood CNS cancer survivors

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This study sought to assess the effects of treatment-induced hearing loss on adult social attainment among adult survivors of childhood cancer treated with plantinum-based chemotherapy and/or cranial radiation.

Audiologic evaluations and questionnaires assessing their perception of social functioning and social attainment (ie, independent living, marriage, and employment) were completed on 180 survivors of pediatric central nervous system (CNS) solid tumors and 226 survivors or non-CNS solid tumors who were treated with potentially ototoxic cancer therapy.

Serious hearing loss was detected in 36% of survivors of CNS tumors and 39% of survivors of non-CNS tumors. The study sample demonstrated an association between treatment-induced hearing loss and both perceived and actual reduced social attainment.

Breast cancer patients may display mild cognitive issues even before chemotherapy.
Effects of treatment-induced hearing loss on adult social attainment among adult survivors of childhood cancer.
Survivors of childhood cancer who are treated with platinum-based chemotherapy and/or cranial radiation are at risk of treatment-induced hearing loss. However, the effects of such hearing loss on adult social attainment have not been well elucidated.
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