Survivors of head, neck cancers almost twice as likely to die from suicide as survivors of other cancers.
A prospective study collected data on the impact of the ACA on percent insured and outcomes for patients with HNSCC in the first years of healthcare law.
Results of a population-based survey, presented at the 2018 ASCO Quality Care Symposium, revealed patients' perceptions regarding choice of treatment of differentiated thyroid cancer (DTC).
Researchers report on the effectiveness results of the Supportive Care of Oncology Patients (SCOOPs) Program were presented at the 2018 ASCO Quality Care Symposium.
Oral care by a dentist was found to reduce pathogenic bacterial plaque thereby decreasing the risk of postoperative pneumonia, a potentially fatal adverse effect, in patients undergoing surgical procedures for cancer.
Researchers conducted a cross-sectional study to determine the incidence and effect of late lower cranial neuropathies on survivors of oropharyngeal cancers.
Updates on the Clinical Diagnosis and Management of Ocular Sebaceous Carcinoma: a Brief Review of the Literature
[OncoTargets and Therapy] Disease specifics, demographics, clinical presentation, and pathology, plus diagnosis and management of ocular SC are highlighted and discussed, including recent advances in management of this aggressive malignancy.
In a retrospective study, researchers used established tools to measure the nutritional status of patients with head and neck cancer before, immediately after, and at 2 follow-up points after radiotherapy.
Navigating Patients With Head and Neck Cancer: Important Roles and Responsibilities of the Oncology Nurse Navigator
The head and neck oncology nurse navigator (ONN) is a unique and critical position to help patients, their families, and their caregivers as they face their diagnosis and undergo treatment.
A review of current options and ongoing trials for managing ARIE, a common esophageal adverse effect caused by radiotherapy to the thoracic region for lung, breast, or head and neck cancers, or lymphoma.
Researchers evaluated whether the development of irAEsc among patients with metastatic head and neck cancer who have failed platinum-based chemotherapy could improve patient outcomes.
Study results presented at 2018 ASCO Annual Meeting demonstrated effectiveness of ado-trastuzumab emtansine in non-breast non-gastric HER2-amplified cancers.
A study presented at the 2018 ONS Annual Congress explored whether patients can safely bypass SICU after HNC surgery, transferring directly from PACU to a specialized unit within the SO.
A link between visual function, ocular symptoms, and quality of life was found in cross-sectional study of patients who underwent radiotherapy for head and neck cancers, according to a presentation at the 2018 ONS Annual Congress.
FDA grants approval to immunotherapy combination in the treatment of unresectable and metastatic BRAF V600E mutation-positive anaplastic thyroid cancer (ATC).
Using the NEI-VFQ-25, researchers assessed vision-targeted health-related quality of life for survivors of retinoblastoma.
A retrospective study demonstrates an increase in HPV16-positive status among patients with OPSCC and a corresponding increase in age at diagnosis.
Results of a retrospective review assessing the prevalence of chronic opioid use among patients with oropharynx cancer after surgery was presented at the 2018 American Head & Neck Society Annual Meeting.
In a phase 2 study, researchers sought to determine the effectiveness of adding HMB/Arg/Gln to cisplatin-based chemoradiotherapy for patients with head and cancers to prevent CRT-induced oral mucositis.
In a study from the Cleveland Clinic, researchers investigated the association between well-differentiated thyroid cancer and risk for AML or CML in those patients treated with radioactive iodine.
Researchers compared opioid use between head and neck cancer (HNCA) and lung or colon cancer (LCCA) cohorts.
Study results show the effect on high-grade toxicity when 5-FU is replaced with docetaxel in the EXTREME regimen in the palliative treatment of patients with metastatic SCCHN.
This study sought to determine if continuing preoperative aspirin therapy would increase the risk of bleeding complications in patients undergoing thyroid surgery.
Study compared the effect of treatments on quality of life in treatment-naïve patients with HNC vs those who underwent radiotherapy and/or chemotherapy, and compared with cancer-free patients.
[Cancer Management and Research] Radiation dose, fractionation strategies, and predictive factors of response to therapy in patients with esophageal carcinoma are reviewed to determine if more intense local therapy would lead to better outcomes and for which patients.
In this study, researchers sought to determine the effect depressive symptoms during treatment planning had on immediate and long-term outcomes for patients with head and neck cancer.
Papillary thyroid cancer patients with LND 0.19 have worse disease-specific, overall survival, researchers found.
Periodontal pathogen Tannerella forsythia linked to increased risk of esophageal adenocarcinoma
Using the statewide Utah Population Database, investigators sought to determine the long-term effects of thyroid cancer on survivors who were younger than 40 years at diagnosis.
Data on psychosocial and psychiatric variables of patients with HNC prior to treatment was analyzed to determine the extent of cognitive impairment and quality of life for patients with head and neck cancer, and its impact on patient outcomes.
Using a data sample from the CDC National Program for Cancer Registries, investigators determined how demographic factors — age, race, and sex — impact 5-year survival rates for HPV-associated cancers from initial diagnosis until death.
Patients with head and neck cancer treated at hospitals attaining the combined metric of a 90 percent or higher negative margin rate and 80% percent of cases achieving a LNY of 18 or more experienced a significant reduction in mortality.
Aggressive de-escalation of chemoradiation after surgery in patients with HPV-associated OPSCC led to similar disease control and improved quality of life and safety profile compared with historical controls, according to data presented at the ASTRO 59th Annual Meeting.
A quality improvement project demonstrates that routine distress assessment using the NCCN DT/PL in patients with head and neck cancers improves referrals for psychosocial services.
The researchers found that the majority of patients had no frank detectable cognitive impairment after undergoing skull base irradiation.
Resistance Training, Nutritional Interventions Prevent Muscle Loss During, After Radiotherapy for Head and Neck Cancer
Intervention with resistance training and nutritional supplements during and after radiation therapy is not only feasible, but also shown to prevent loss of muscle mass and improve quality of life in patients with head and neck cancer (HNC).
Risk of Thyroid Cancer Increased With Fruit Juice Consumption, No Effect With Fruit and Vegetable Consumption
No correlation was found between fruit and vegetable consumption and the risk of differentiated thyroid cancer, but a positive trend may be associated with fruit juice intake.
Lenvatinib Improves OS, PFS in Radioiodine-Refractory Differentiated Thyroid Cancer in All Older Patients
Results from a sub-analysis of the impact of age on the safety and efficacy of lenvatinib in patients with RR-DTC in the SELECT trial showed that lenvatinib significantly increased PFS.
Immunotherapy regimens FDA-approved for the treatment of melanoma may also be an option for a rare and aggressive form of papillary thyroid cancer.
Small study also showed that pembrolizumab does not significant impair radiation or chemotherapy dosing.
Study also provides evidence supporting an anti-tumor effect associated with a single preoperative dose of pembrolizumab.
Combining extracorporeal shock wave (ESW) technique with nanoparticle delivery improves treatment of difficult-to-treat solid tumors, such as anaplastic thyroid cancer.
Although screening is often recommended as the first line of prevention for most cancers, recent recommendation from the USPSTF advises against thyroid cancer screening in nonsymptomatic adults.
Disease-specific survivorship care plans (SCPs) for head and neck cancer support a successful transition to a healthy lifestyle after curative intent therapy of larynx and oral cavity/pharynx cancer.
A literature review noted improvements in quality of life after patients were coached and educated following radiotherapy for HPV-associated oropharyngeal cancers.
Clinical practice guideline from ASTRO addresses optimal radiation doses and fractionation schedules, integrating therapies, and induction chemotherapy for oropharyngeal squamous cell carcinoma (OPSCC).
Thyroid is more likely to be managed with surgical intervention when patients have access to expanded health insurance.
A report on incidence of thyroid cancer shows incidence of the disease is increasing among certain populations: younger persons, Hispanic, and African American.
Continuing immunotherapy after disease progression extends survival for some patients with head and neck cancer.
Protein produced by chronically infected cells in persons with HPV16 infection serves as a biomarker for risk of cancer of the oropharynx.
Thymomas can result in a newly described autoimmune disease, potentially leading to hypopituitarism,
Deciding not to intervene for small, incidentally identified thyroid cancer may cause patients to experience anxiety and feelings of isolation.
The top reasons for not initiating HPV vaccination are necessity, safety, and knowledge, rather than a lack of discussions on sexuality.
ASCO endorses ACS head and neck survivorship care guideline, which supports health promotion, especially regarding tobacco cessation and dental care.
Oncology nurse navigators improved physician engagement in multidisciplinary discussions prior to the initiation of treatment for patients with head and neck cancer.
A new approach in which patients receive a single dose of chemotherapy may greatly improve the laryngeal cancer survival rate.
Investigators determined the impact of socioeconomic status on disease status at presentation and survival among patients with head and neck squamous cell carcinoma.
The impact of oral squamous cell carcinoma (OSCC) diagnosis and treatment on sexual behavior and relationship stress with respect to HPV status was evaluated in this study. Participants included patients with HPV-positive and HPV-negative disease, as well as partners.
Bioselection-individualized Treatment Modality Selection Improves Advanced Laryngeal Cancer Survival
Multivariate analysis indicates that disease-specific survival of individuals with advanced laryngeal cancer was improved for those receiving neoadjuvant therapy.
Twenty-three percent of patients with HNSCC had CVD at the time of their diagnosis.
Researchers reveal that miR-17 appears to be important in driving esophageal tumor resistance to radiotherapy.
Findings at 6 and 12 months after treatment for advanced head and neck cancer indicate a higher risk of recurrences for those reporting cachexia after their treatment.
High pretreatment uric acid may be a clinical biomarker for lung metastasis.
For patients with head and neck or lung cancer, stepped care programs may offer a more affordable yet effective approach.
Progression-free survival with panitumumab plus accelerated-fractionation radiotherapy was compared with that of cisplatin plus standard-fractionation radiotherapy in patients with locoregionally advanced HNSCC in a recently published study.
Widespread routine thyroid cancer screening can lead to overdiagnosis and overtreatment, the USPSTF contends.
A retrospective evaluation investigated the association between risk of esophageal cancer, metabolic syndrome, Barrett esophagus, and GERD in older persons.
Smoking-attributable cancer mortality estimates have not been established by state; therefore, in this study, the proportion of cancer deaths among persons 35 years and older related to cigarette smoking in 2014 was calculated for each state and DC.
Patients with oropharyngeal tumors that harbor HPV16 have higher 5-year survival and lower recurrence rates than patients with tumors that harbor other HPV strains or are HPV-negative.
Patients with head and neck cancer treated with IMRT had a significantly shorter duration of feeding tube placement compared with those who received 3DRT.
Transoral robotic surgery (TORS) with or without radiation therapy or chemotherapy is an effective treatment option for patients with oropharyngeal cancer regardless of their p16 status.
[Journal of Gastrointestinal Oncology] This research examines factors associated with survival in patients with brain metastasis from esophageal cancer.
Despite a higher risk for HPV-negative orophayngeal squamous cell carcinoma (OPSCC), poor oral health appears to be associated with OPSCC regardless of HPV status.
Gemcitabine in combination with cisplatin is associated with a significant improvement in progression-free survival in nasopharyngeal carcinoma.
Quality of Life and Cosmetic Result of Single-port Access Endoscopic Thyroidectomy via Axillary Approach in Patients with papillary thyroid carcinoma
[OncoTargets and Therapy] This research reviews the effects of single-port access transaxillary totally endoscopic thyroidectomy on outcomes following surgery, including quality of life and cosmetic result, in patients with papillary thyroid carcinoma (PTC).
Patients with medullary thyroid cancer who harbor RET M918T or RAS mutations may derive greater clinical benefit from cabozantinib compared with patients who do not have those genetic mutations.
In contrast of available prospective data, most older patients with locoregionally advanced head and neck cancer are treated with definitive radiotherapy also receive systemic therapy.
Chemoradiation Combination Could Preserve Larynx in Patients With Laryngeal and Hypolaryngeal Cancer
Researchers assessed the rates of laryngeal preservation and laryngectomy-free survival in patients with laryngeal or hypopharyngeal cancer who received the monoclonal antibody cetuximab and radiation therapy or radiation therapy alone.
Methadone appears to be superior to fentanyl for the treatment of neuropathic pain in patients with head and neck cancer.
A recent study examined the possible correlation between Medicaid coverage status and overall survival for patients with head and neck cancer.
There were no effective therapeutic options for advanced thyroid cancer until 5 years ago.
The incidence of oropharyngeal squamous cell carcinoma is increasing among older patients residing in the United States, likely due to the increase in HPV-associated malignancies.
Beverages derived from broccoli sprout extracts were found to have preclinical chemopreventive activity against oral cancer induced by carcinogens.
Quality of life for patients with oral cancer can be dismal due to cancer-related pain. An NIDCR grant is supporting the investigation of a nonviral gene delivery method for treating oral cancer pain safely and effectively.
Scientists developed an innovative nanoplatform to more effectively deliver RNA interference to anaplastic thyroid cancer (ATC) sites. ATC is the most aggressive form of thyroid cancer; mortality is almost 100% and median survival is 3 to 5 months.
Stepped care is effective and reduces recovery time among patients with head and neck cancer or lung cancer and untreated psychological distress.
Nimotuzumab + Radiotherapy Less Toxic Than Cisplatin + Radiotherapy for Stage III/IVB Nasopharyngeal Cancer
Patients with locally advanced nasopharyngeal cancer concurrently treated with nimotuzumab and radiotherapy had similar rates of progression-free and overall survival to those treated with cisplatin and radiotherapy, but with significantly fewer GI and hematologic toxicities, according to phase 3 trial results presented at the ASCO 2016 Annual Meeting.
Survival results from the first randomized phase 3 trial to compare cisplatin-radiotherapy with cetuximab-radiotherapy after induction chemotherapy in patients with locally advanced unresectable head and neck cancer remain inconclusive, with both arms showing good locoregional control, greater than 50% at 3 years, attendees at the ASCO 2016 Annual Meeting were told.
A phase 3 noninferiority study has found that in patients with nonoperable locally advanced squamous cell cancer of the head and neck, concurrent chemoradiotherapy remains the standard treatment, according to results presented at the ASCO 2016 Annual Meeting.
The immunotherapy drug nivolumab conferred a survival benefit in patients with head and neck cancer over standard chemotherapy.
Incorporating a modified MASCC grading tool for evaluating epidermal growth factor receptor inhibitor (EGFRI) toxicities and quality of life improved the rate of skin assessments and documentation.
Oncology Nurse-led Team Can Reduce Treatment Delays, Hospitalizations for Patients With Head and Neck Cancer
An oncology nurse-led team approach can reduce treatment delays and hospitalizations and improve quality of care for patients with head and neck cancer.
The effectiveness of chemotherapy was enhanced by targeting survivin, a protein that inhibits apoptosis or cell death, according to preclinical research in cells and mouse models of retinoblastoma.
Having an unplanned readmission within 30 days of undergoing definitive surgery is associated with increased risk of 30-day mortality among patients with previously untreated parotid cancer.
In women of reproductive age who have thyroid cancer, their remaining egg supply is affected by radioactive iodine treatment, potentially reducing their fertility.
Patients age 65 years or older with recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC) did not have worse clinical outcomes.
Posttreatment image-guided surveillance achieved similar survival rates as planned neck dissection in patients with head and neck.
A new guideline from the American Cancer Society provides recommendations on follow-up care for survivors of head and neck cancer.
Similar survival seen for PET-CT-guided surveillance and planned neck dissection, but fewer operations.
Wellness programs offering a variety of supportive tools are needed for caregivers of patients with head and neck cancer.
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