General Oncology

The Efficacy and Safety of Apatinib for Refractory Malignancies: A Review and Meta-analysis

The Efficacy and Safety of Apatinib for Refractory Malignancies: A Review and Meta-analysis

[OncoTargets and Therapy] A meta-analysis sought to support the efficacy and safety of apatinib in the treatment of solid tumors that was previously reported in previous studies.

Study Reveals Relationship of Sleep Duration, Diabetes Risk in Cancer Survivors

Study Reveals Relationship of Sleep Duration, Diabetes Risk in Cancer Survivors

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In a review of data from the National Health Interview Survey, researchers identified the relationship between short and long sleep durations and diabetes in cancer survivors.

Medication, Vaccination Uptake Improved by Involving Pharmacists in Elder Cancer Care

Medication, Vaccination Uptake Improved by Involving Pharmacists in Elder Cancer Care

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Researchers explored the feasibility of integrating pharmacists into the oncology care team for older patients with cancer to determine the impact this intervention would have on medication management and vaccination uptake.

Chemoimmunotherapy prolongs PFS in metastatic triple-negative breast cancer

Chemoimmunotherapy prolongs PFS in metastatic triple-negative breast cancer

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A prospective analysis of patients with advanced cancer revealed the effect delirium has on palliative care and symptom management at baseline and after 7 days of treatment.

PACC Guidelines Recommend IT Morphine, Ziconotide for Chronic Pain 

PACC Guidelines Recommend IT Morphine, Ziconotide for Chronic Pain 

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The 2016 evidence-based PACC guidelines recommend the use of morphine and ziconotide as effective and safe first-line IT monotherapies for chronic pain.

Cell Phones and Cancer Risk (Fact Sheet)

Cell Phones and Cancer Risk (Fact Sheet)

This fact sheet explores the technology of cell phones, radiofrequency energy and how it may affect the body, and the findings of research studies about cell phone exposure and cancer risk.

ASCO, SITC Release Recommendations for Clinical Trial Reporting of Immunotherapy Adverse Events

ASCO, SITC Release Recommendations for Clinical Trial Reporting of Immunotherapy Adverse Events

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As immunotherapies gain a stronger foothold as a treatment option for cancer, ASCO and SITC convened a panel to develop recommendations to ensure consistent and efficient clinical trial reporting in immuno-oncology.

Standardization Could Improve Tumor Board Interpretation, Recommendations

Standardization Could Improve Tumor Board Interpretation, Recommendations

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Using fictional patient profiles and a questionnaire on recommendation procedures, researchers were able to demonstrate a need for standardized tumor board interpretation and recommendation processes worldwide.

Postoperative Radiotherapy Favorable as Adjuvant Treatment for Thymic Neuroendocrine Tumors

Postoperative Radiotherapy Favorable as Adjuvant Treatment for Thymic Neuroendocrine Tumors

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A propensity-score matched analysis was used to determine the effect of surgery and postoperative radiotherapy in patients with TNETs.

Nedaplatin Associated With Less Toxicity Than Cisplatin for MPE

Nedaplatin Associated With Less Toxicity Than Cisplatin for MPE

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In this retrospective study, researchers sought to determine the efficacy of nedaplatin vs cisplatin for the treatment of malignancy-induced malignant pleural effusion.

Chemotherapy Side Effects in Women vs Men: Broader Range, More Severe

Chemotherapy Side Effects in Women vs Men: Broader Range, More Severe

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An analysis of pooled data from 4 randomized controlled clinical trials revealed that male and female patients experience different chemotherapy side effects and at different severities, according to a poster presented at ESMO 2018 Congress.

Light Use of Topical Skin Treatments Before Radiotherapy Appears Safe

Light Use of Topical Skin Treatments Before Radiotherapy Appears Safe

Radiation dose not impacted with light or moderate use of skin treatments, regardless of beam energy, incidence.

Adjusting Etoposide Dose When Used With Prezcobix

Adjusting Etoposide Dose When Used With Prezcobix

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Do you have any resources that give specific guidelines or even anecdotal sources on how to adjust etoposide dose in a patient taking Prezcobix?

Immune Checkpoint Inhibitor Therapy May Affect Thyroid Function

Immune Checkpoint Inhibitor Therapy May Affect Thyroid Function

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A review of medical records revealed that thyroid function may be affected by immune checkpoint inhibitor therapy, and these patients should undergo thyroid function tests, especially during the first 8 weeks of therapy.

Seeking an Explanation for the Lack of Research Focused in Pediatric Oncology Therapeutics

Seeking an Explanation for the Lack of Research Focused in Pediatric Oncology Therapeutics

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Researchers sought an explanation for the paucity of research, drug development, and clinical trials focusing specifically on cancer in pediatric populations.

Prisoner or Patient? Challenges of Cancer Care in the Incarcerated Population

Prisoner or Patient? Challenges of Cancer Care in the Incarcerated Population

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This in-depth review examines the inherent challenges of providing cancer care for incarcerated patients.

HPV Vaccination and Anti-programmed Cell Death 1 Inhibition Improve Survival in Patients With Invasive HPV-16

HPV Vaccination and Anti-programmed Cell Death 1 Inhibition Improve Survival in Patients With Invasive HPV-16

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In this study, researchers sought to determine if use of a tumor specific vaccine would improve the efficacy of PD-1 immune checkpoint inhibition in patients with incurable HPV-16 cancer.

FDA Approves HPV Vaccine for People Through Age 45

FDA Approves HPV Vaccine for People Through Age 45

Updated vaccine designed to prevent cancers and disease caused by nine HPV types

Advances in Radiogenomics: A Review

Advances in Radiogenomics: A Review

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Researchers are seeking genetic biomarkers that can predict which patients are most likely to suffer radiotoxicities and which can safely undergo intensified radiation treatment regimens.

Frequency of Reclassifications of Genetic Testing Results Is Low

Frequency of Reclassifications of Genetic Testing Results Is Low

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A retrospective analysis of genetic testing results at one laboratory reports that reclassifications occurs in approximately one-quarter of tests, resulting in both downgrades and upgrades of variant classifications.

Delphi Panel Presents Recommendations for Expanding Role of Patients in Research

Delphi Panel Presents Recommendations for Expanding Role of Patients in Research

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A Delphi panel developed recommendations for integrating patients, as well as caregivers and advocate, a greater role in medical research while maintaining scientific integrity of studies.

Number of Health-Related Data Breaches on the Increase

Number of Health-Related Data Breaches on the Increase

The researchers found that individual breaches affected a range of 500 to 78.8 million records.

Integrating Mental Health Into Multidisciplinary Oncology Care Improves Inpatient Care

Integrating Mental Health Into Multidisciplinary Oncology Care Improves Inpatient Care

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In a study presented at the 2018 ASCO Quality Care Symposium, researchers presented study findings that showed adding mental health professionals to the multidisciplinary cancer care team improves identification and treatment of delirium in hospitalized patients.

Crowdfunding for Cancer Treatments Could Exploit Vulnerable Patients

Crowdfunding for Cancer Treatments Could Exploit Vulnerable Patients

Money raised for cancer-related appeals is on the increase; but some money funds alternative therapies that have been discredited.

Tool Addresses Well-being of Informal Caregivers of Patients With Cancer

Tool Addresses Well-being of Informal Caregivers of Patients With Cancer

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In this study, researchers assessed a new tool designed to assess the well-being of cancer patients' informal caregivers.

Immune Checkpoint Inhibitors: A Review of Side Effects, Their Causes and Incidence

Immune Checkpoint Inhibitors: A Review of Side Effects, Their Causes and Incidence

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A multicenter research team determined the incidence and type of fatal toxic effects associated with immune checkpoint inhibitors.

ASCO Roundtable Addresses Clinical Trial Financial Burdens

ASCO Roundtable Addresses Clinical Trial Financial Burdens

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The American Society of Clinical Oncology hosted a roundtable to develop recommendations targeted at improving patients' out-of-pocket costs for clinical trial participation.

United States Senate Passes Opioids Bill

United States Senate Passes Opioids Bill

Comprehensive bipartisan package earmarks billions of dollars to fight opioid abuse in the United States

Communication in Shared Decision-Making in Oncology

Communication in Shared Decision-Making in Oncology

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Researchers investigated the effectiveness of different communication approaches used in shared decision-making with cancer patients.

Endocrine Society Released Guidelines for Managing Endocrine Disorders in Childhood Cancer Survivors

Endocrine Society Released Guidelines for Managing Endocrine Disorders in Childhood Cancer Survivors

Clinical guideline reviews the diagnosis and treatment of hypothalamic-pituitary and growth disorders that are often seen in survivors of childhood cancer.

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