Drug Name:
Felodipine Rx
Generic Name and Formulations:
Felodipine 2.5mg, 5mg, 10mg; ext rel tabs.
Company:
Various generic manufacturers
Therapeutic Use:
Indications for Felodipine:
Hypertension.
Adult:
Take without food or with a light meal. Do not crush or chew. Initially 5mg once daily. Range 2.5–10mg once daily. Adjust at 2 week intervals; max 10mg daily. Elderly or hepatic dysfunction: initially 2.5mg once daily.
Children:
Not recommended.
Warnings/Precautions:
Heart failure. Hepatic impairment. Maintain good dental hygiene. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.
Pharmacological Class:
Calcium channel blocker (CCB) (dihydropyridine).
Interactions:
May increase metoprolol, tacrolimus levels. Potentiated by cimetidine. Increased bioavailability with grapefruit juice. Levels decreased with long-term anticonvulsants (eg, carbamazepine, phenytoin, phenobarbital), consider alternate antihypertensive therapy.
Adverse Reactions:
Peripheral edema, headache, flushing, dizziness, respiratory symptoms, weakness, cough, GI upset, gynecomastia; hypotension, tachycardia, syncope, MI, angina, gingival hyperplasia (rare).
Note:
Formerly known under the brand name Plendil.
How Supplied:
Contact supplier.
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