Miscellaneous ocular agents:
Indications for UPNEEQ:
Instill one drop into one or both ptotic eye(s) once daily.
<13yrs: not established.
Severe or unstable/uncontrolled cardiovascular disease. Orthostatic hypotension. Uncontrolled hypertension or hypotension. Cerebral or coronary insufficiency. Sjögren's syndrome. Increased risk of angle closure glaucoma. Contact lenses (remove; may reinsert 15mins after administration). Pregnancy. Nursing mothers.
Caution with concomitant beta-blockers, antihypertensives, cardiac glycosides, alpha-1 receptor antagonists. Concomitant MAOIs may affect the metabolism and uptake of circulating amines; caution. Allow ≥15mins between dosing of other ophthalmic drugs.
Punctate keratitis, conjunctival hyperemia, dry eye, vision blurred, instillation site pain, eye irritation, headache.
Generic Drug Availability:
Single patient-use containers—15, 30