Indications for PERSANTINE:
Adjunct to oral anticoagulants after cardiac valve replacement to prevent thromboembolism.
75mg–100mg four times a day.
Severe coronary artery disease (eg, unstable angina, recent MI). Hypotension. Potential hepatic insufficiency. Interrupt dose for 48hrs prior to stress testing (w. IV dipyridamole, other adenosinergic agents). Pregnancy. Nursing mothers.
May potentiate cardiovascular effects of IV adenosinergic agents (eg, adenosine, regadenoson). May antagonize cholinesterase inhibitors.
Dizziness, abdominal distress, headache, rash.