Smoking:

Indications for NICOTROL NS:

Adjunct in smoking cessation therapy.

Adult:

Do not sniff, swallow, or inhale. Individualize. Usually 1–2 doses/hour; max 5 doses/hour, 40 doses/day for up to 3 months; may discontinue abruptly or taper.

Children:

Not recommended.

Contraindications:

Concurrent smoking or other nicotine products.

Warnings/Precautions:

Sustained use (>6 months): not recommended. Avoid immediately post-MI, in arrhythmias, or severe or worsening angina pectoris. Hypertension. Vasospastic or coronary heart disease. Bronchospastic disease. Severe reactive airway disease: not recommended. Hepatic or moderate/severe renal impairment. Hyperthyroidism. Pheochromocytoma. Diabetes. Esophagitis. Active gastric or peptic ulcers. Elderly. Low doses may be toxic to children and pets. Nasal Spray: nasal mucosal disorders. Pregnancy, labor & delivery: not recommended (attempt nondrug treatment first). Nursing mothers.

See Also:

Interactions:

Nasal Spray antagonized by nasal vasoconstrictors (eg, xylometazoline). Smoking cessation potentiates theophylline, insulin, β-blockers, pentazocine, oxazepam, tricyclic antidepressants (eg, imipramine), caffeine, acetaminophen, adrenergic antagonists (eg, prazosin, labetalol), others. Smoking cessation antagonizes adrenergic agonists (eg, isoproterenol, phenylephrine), others.

Adverse Reactions:

Local irritation, nausea, diarrhea, hiccup, dyspepsia, headache, dizziness, palpitations, hypertension.

How Supplied:

Inhaler 168 cartridges—1 (w. mouthpieces and case); Nasal Spray 10mL (200 sprays)—4 (w. metered spray pump)