• Anorexia/cachexia

Anorexia/cachexia:

Indications for Megestrol Oral Suspension:

Anorexia, cachexia, or unexplained significant weight loss in patients diagnosed with AIDS.

Adult:

Initially 800mg/day.

Children:

Not established.

Contraindications:

Pregnancy.

Warnings/Precautions:

Do not substitute with other megestrol suspensions (not interchangeable). History of thromboembolic disease. Monitor for signs/symptoms of adrenal insufficiency; consider empiric therapy if occurs. Diabetes. Renal impairment. Elderly. Fetal toxicity. Obtain (–) pregnancy test prior to initiation. Advise females of reproductive potential to use effective contraception during therapy. Nursing mothers: not recommended.

Pharmacologic Class:

Progestin.

Interactions:

May increase insulin requirements. Monitor INR closely with warfarin.

Adverse Reactions:

GI upset, impotence, flatulence, rash, hypertension, fever, decreased libido, breakthrough bleeding, hyperglycemia, insomnia.

How Supplied:

Contact supplier.