Acne:

Indications for: ACZONE

Acne vulgaris.

Adult Dosage:

Wash skin and pat dry. Apply pea-sized amount to affected area in a thin layer twice daily in the AM & PM. Rub in gently and completely. Wash hands after use. Reevaluate if no improvement after 12 weeks.

Children Dosage:

<12yrs: not recommended.

ACZONE Warnings/Precautions:

Avoid in congenital or idiopathic methemoglobinemia. G6PD deficiency: may have increased risk of methemoglobinemia or hemolytic anemia; discontinue if occurs. Pregnancy. Nursing mothers.

See Also:

ACZONE Classification:

Sulfone.

ACZONE Interactions:

Increased risk of hemolysis in G6PD-deficient patients with concomitant trimethoprim/sulfamethoxazole, other folic acid antagonists (eg, pyrimethamine), anticonvulsants, rifampin, St. John's wort. Increased risk of methemoglobinemia with concomitant sulfonamides, acetaminophen, chloroquine, nitrates, nitrites, nitrofurantoin, phenobarbital, phenytoin, primaquine, quinine, and others. Skin/hair discoloration with topical benzoyl peroxide.

Adverse Reactions:

Application site reactions (oiliness, peeling, dryness, erythema, pruritus).

Generic Drug Availability:

NO

How Supplied:

Gel 5% (tubes)—30g, 60g, 90g; Gel 7.5% (pumps)—30g, 60g, 90g