More Adverse QOL Issues in Young Breast Cancer Patients

This article originally appeared here.
Share this content:
More Adverse QOL Issues in Young Breast Cancer Patients
More Adverse QOL Issues in Young Breast Cancer Patients

WEDNESDAY, Jan. 25 (HealthDay News) -- Younger women with breast cancer experience a decrease in their health-related quality of life (QOL), including increased psychological distress and fertility-related concerns, according to a review published Jan. 23 in the Journal of the National Cancer Institute.

Jessica Howard-Anderson, of the University of California Los Angeles, and colleagues conducted a systematic literature review to investigate health-related QOL, menopausal symptoms and fertility concerns, and behavioral health outcomes for younger breast cancer survivors. Twenty-eight articles (15 cross-sectional studies, eight longitudinal studies, and five randomized trials) were included, which exclusively analyzed female breast cancer survivors who were aged 50 years or younger, or premenopausal, at diagnosis.

The researchers found that worse QOL outcomes were more frequent or severe in younger breast cancer survivors (aged ≤50 years) when compared with the general age-matched population of women without cancer and to older women with breast cancer (aged >50 years). In younger women, concerns about premature menopause, menopausal symptoms, and infertility were common, and affected the level of distress experienced following treatment. In younger women, weight gain and physical inactivity were frequent health outcomes.

"Younger women with breast cancer were found to experience distinct psychosocial and menopause-related concerns, weight gain, and physical inactivity. A need for more longitudinal research, including efforts at intervention to manage these symptoms and adverse health outcomes, remains," the authors write.

Full Text (subscription or payment may be required)

You must be a registered member of ONA to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings


Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs