Fish oil diet proves beneficial for prostate cancer

This article originally appeared here.
Share this content:
Low-Fat Fish Oil Diet Beneficial in Prostate Cancer
Low-Fat Fish Oil Diet Beneficial in Prostate Cancer

(HealthDay News) -- In men with prostate cancer, a low-fat fish oil diet is associated with lower serum levels of pro-inflammatory molecules, changes in serum levels of omega fatty acids, and a lower measure of cancer growth, compared with a Western diet, according to a study published online Oct. 29 in Cancer Prevention Research.

Colette Galet, Ph.D., from the University of California in Los Angeles, and colleagues compared serum levels of fatty acids and pro-inflammatory eicosanoids as well as cell cycle progression score in men with prostate cancer who had been randomly assigned to a low-fat fish oil diet (20 percent of calories from fat) or a Western diet (40 percent of calories from fat) for four to six weeks.

The researchers found that men on the fish oil diet had significantly lower serum levels of omega-6 fatty acids and 15(S)-hydroxyeicosatetraenoic acid (HETE), higher serum levels of omega-3 fatty acids, and a significantly lower cell cycle progression score compared with men on a Western diet. Leukotriene B4 levels were similar in both groups.

"In conclusion, a low-fat fish oil diet resulted in decreased 15(S)-HETE levels and lower cell cycle progression score relative to a Western diet," Galet and colleagues write.

The study was the result of work supported with resources and the use of facilities at Myriad Genetics Laboratories.

Full Text (subscription or payment may be required)

You must be a registered member of ONA to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings


Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs