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Sexual Aids and Resources Not Readily Available at Cancer Centers

Sexual Aids and Resources Not Readily Available at Cancer Centers

Most centers reported having no sexual aids available for patients, according to researchers.

Cisplatin-Induced Adverse Events in Osteosarcoma Not Improved With Pantoprazole

Cisplatin-Induced Adverse Events in Osteosarcoma Not Improved With Pantoprazole

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This phase 2 study sought to determine whether concurrent pantoprazole would improve cisplatin-induced ototoxicity and nephrotoxicity in younger patients with osteosarcoma.

Induced Pluripotent Stem Cell Vaccine May Help Prevent Tumor Growth

Induced Pluripotent Stem Cell Vaccine May Help Prevent Tumor Growth

iPSC vaccine prevented tumor growth in syngeneic murine breast CA, mesothelioma, melanoma models

Gas Mixture Improves Efficacy of Breakthrough Cancer Pain Treatment

Gas Mixture Improves Efficacy of Breakthrough Cancer Pain Treatment

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Patient self-administration of a nitrous oxide/oxygen combination appears to be superior to oxygen alone as an adjunct analgesic treatment for severe breakthrough cancer pain.

Obesity, Male Gender May Improve Survival Outcomes with Targeted and Immunotherapy in Melanoma

Obesity, Male Gender May Improve Survival Outcomes with Targeted and Immunotherapy in Melanoma

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A retrospective study evaluated the relationship of BMI with survival outcomes among patients with metastatic melanoma who received targeted therapy, immunotherapy, or chemotherapy.

Apalutamide Prolongs Time to Metastasis in Castration-resistant Prostate Cancer

Apalutamide Prolongs Time to Metastasis in Castration-resistant Prostate Cancer

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SPARTAN phase 3 study shows that apalutamide prolongs metastasis-free survival and time to symptomatic progression compared with placebo among men with nonmetastatic CRPC.

FDA Upgrades Nivolumab to Regular Approval for Adjuvant Treatment of Advanced Melanoma

FDA Upgrades Nivolumab to Regular Approval for Adjuvant Treatment of Advanced Melanoma

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The FDA granted approval for nivolumab for adjuvant treatment of some patients with melanoma, based on the results of the CHECKMATE-238 study.

Self-Predictions for Well-Being Influence Satisfaction After Mastectomy, Breast Reconstruction

Self-Predictions for Well-Being Influence Satisfaction After Mastectomy, Breast Reconstruction

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Observational study assessed the influence of patients' self-predictions for well-being after undergoing mastectomy for breast cancer with or without immediate breast reconstruction.

Susceptibility Gene Mutations Common in Those With Pancreatic Cancer and History of Other Cancers

Susceptibility Gene Mutations Common in Those With Pancreatic Cancer and History of Other Cancers

Those with pancreatic adenocarcinoma and a personal history of another cancer associated with hereditary breast and ovarian cancer or Lynch syndrome may be more likely to carry germline mutations.

Axitinib Plus Pembrolizumab Shows Promise in Treatment-Naïve Advanced RCC

Axitinib Plus Pembrolizumab Shows Promise in Treatment-Naïve Advanced RCC

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Nonrandomized trial demonstrates tolerability and antitumor activity of a PD-1 checkpoint inhibitor plus a VEGF-TKI in patients with treatment-naïve advanced RCC.

Self-guided Cognitive Behavioral Pain Management Shows Efficacy in Painful CIPN

Self-guided Cognitive Behavioral Pain Management Shows Efficacy in Painful CIPN

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Self-guided online cognitive behavioral pain management may result in improved "worst" pain but not "average" pain compared with usual care for the treatment of painful chemotherapy-induced peripheral neuropathy.

Chronic Disease Major Factor for Cancer Risk and Cancer Mortality

Chronic Disease Major Factor for Cancer Risk and Cancer Mortality

Risk scores summarizing eight diseases, markers tied to cancer risk in dose-response manner

Sex, Age Associated With Mortality Risk in Renal Cell Cancer Treated With VEGF-TKIs

Sex, Age Associated With Mortality Risk in Renal Cell Cancer Treated With VEGF-TKIs

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Phase 3 study sought to assess the associations between adjuvant therapy with VEGF-tyrosine kinase inhibitors (TKIs) and benefit, sex, and age in patients with resected renal cell cancer.

Antibiotics May Reduce Treatment-Related Issues in Renal Cell Carcinoma

Antibiotics May Reduce Treatment-Related Issues in Renal Cell Carcinoma

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Researchers evaluated the effect of antibiotics on treatment delays, interruptions, and dose reductions in patients with mRCC treated with a first-line VEGF-TKI and presented their results at the 2018 Genitourinary Cancers Symposium.

Potential for Metastatic Melanoma Cure Seen in High CR Rate With Pembrolizumab

Potential for Metastatic Melanoma Cure Seen in High CR Rate With Pembrolizumab

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Baseline tumor size and PD-L1 status were independently associated with the likelihood of a complete response.

Daily IGRT Regimen for Prostate Cancer Improves Rectal Toxicity, Not OS

Daily IGRT Regimen for Prostate Cancer Improves Rectal Toxicity, Not OS

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Researchers present findings of a comparison of daily image-guided radiotherapy (IGRT) vs a weekly regimen in patients with N0 localized prostate cancer at the 2018 GU Cancers Symposium.

Active Surveillance, Repeat Biopsies Not Linked to Post Prostatectomy Complications

Active Surveillance, Repeat Biopsies Not Linked to Post Prostatectomy Complications

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Rates of erectile dysfunction and urinary incontinence at 1, 2, and 3 years after radical surgery are not higher among men who have multiple prostate biopsies while on active surveillance for prostate cancer.

Pomalidomide Plus Dexamethasone Effective in R/R Multiple Myeloma

Pomalidomide Plus Dexamethasone Effective in R/R Multiple Myeloma

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Researchers report on their findings of a retrospective study that compared pomalidomide plus dexamethasone vs dexamethasone alone in patients with relapsed/refractory multiple myeloma.

As Patients, Nurses Rate Their Care Satisfaction as Moderate

As Patients, Nurses Rate Their Care Satisfaction as Moderate

Study findings indicate that nurses have lower ratings of satisfaction with care than those given by the general public.

Survival Trends for Cancer on the Increase Worldwide

Survival Trends for Cancer on the Increase Worldwide

Increasing trend seen for some lethal cancers, with up to 5 percent increase for liver, pancreas, lung CAs

Tisagenlecleucel Produces Durable Remissions in Pediatric, Young Adult B-cell ALL

Tisagenlecleucel Produces Durable Remissions in Pediatric, Young Adult B-cell ALL

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A previous single-site trial showed that patients with R/R B-cell ALL treated with tisagenlecleucel achieved high complete remission rates. In this study, investigators report on results after the scope of the study was expanded.

Early Integration of Palliative Care Improves Quality of Life in Advanced Cancer

Early Integration of Palliative Care Improves Quality of Life in Advanced Cancer

Results of a nonblinded study demonstrate the value of incorporating early palliative care into oncologic care for patients with advanced cancer.

High Opioid Use Linked to Shorter Cancer Survival, Increased Health Care Use

High Opioid Use Linked to Shorter Cancer Survival, Increased Health Care Use

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Researchers sought to determine the link between opioid use among patients with advanced cancer and health care use such as urgent care, inpatient, and emergency room visits.

Preoperative Treatment for Gastric Cancer Varies by Race, Ethnicity

Preoperative Treatment for Gastric Cancer Varies by Race, Ethnicity

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Researchers conducted a retrospective study of US patients with gastric cancer to determine what factors influenced the use of preoperative chemotherapy in this patient population.

Platinum-Based Chemotherapies Demonstrate Similar Risk for Thromboembolic Events

Platinum-Based Chemotherapies Demonstrate Similar Risk for Thromboembolic Events

Platinum-based chemotherapy agents for lung cancer may increase the risk for thromboembolism.

Breast Cancer Therapies Associated With Increased Risk for Cardiovascular Disease

Breast Cancer Therapies Associated With Increased Risk for Cardiovascular Disease

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Advances in breast cancer treatment are improving outcomes for patients with the disease; however, treatments are increasing these patients' risk for cardiovascular diseases.

Documentation of Cancer Risk in Indeterminate Pulmonary Nodules Inconsistent

Documentation of Cancer Risk in Indeterminate Pulmonary Nodules Inconsistent

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Qualitative risk statements of malignancy for indeterminate pulmonary nodules are imprecise, highly variable, and should be replaced by a standard scale.

Cardiotoxicity Risk Greater in Blacks With Breast Cancer Receiving HER2 Therapies

Cardiotoxicity Risk Greater in Blacks With Breast Cancer Receiving HER2 Therapies

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Retrospective study examines the association between risk of cardiotoxicity and race in women with breast cancer receiving chemotherapy and at least 1 year of HER2-targeted therapy.

Adjuvant Radiotherapy Found Superior to Early-Salvage RT in Prostate Cancer

Adjuvant Radiotherapy Found Superior to Early-Salvage RT in Prostate Cancer

Propensity score-matched study compared adjuvant radiotherapy with surveillance and early-salvage radiotherapy after prostatectomy in men with prostate cancer.

Oral Impairment Linked to Reduced QOL in Posttherapy Head and Neck Cancer

Oral Impairment Linked to Reduced QOL in Posttherapy Head and Neck Cancer

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Study compared the effect of treatments on quality of life in treatment-naïve patients with HNC vs those who underwent radiotherapy and/or chemotherapy, and compared with cancer-free patients.

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