Drug Name:
CORZIDE Rx
Generic Name and Formulations:
Nadolol, bendroflumethiazide; 40mg/5mg, 80mg/5mg; scored tabs.
Company:
Pfizer Inc.
Therapeutic Use:
Indications for CORZIDE:
Hypertension.
Adult:
Titrate components. Renally impaired: increase dosing interval; see literature.
Children:
Not recommended.
Contraindications:
Asthma. Sinus bradycardia. 2nd- or 3rd-degree AV block. Overt heart failure. CHF. Cardiogenic shock. Anuria. Sulfonamide allergy.
Warnings/Precautions:
Ischemic heart disease. Bronchospastic disease, COPD. Renal or hepatic dysfunction. Gout. Diabetes. Postsympathectomy. Hyperthyroidism. Monitor electrolytes, renal function. Surgery. SLE. Avoid abrupt cessation. Pregnancy (Cat.C). Nursing mothers: not recommended.
Pharmacological Class:
Noncardioselective beta-blocker + diuretic.
Interactions:
Hypotension with alcohol, CNS depressants, MAOIs, prazosin, other antihypertensives. Bradycardia with catecholamine-depleting drugs. Adjust antidiabetic, anticoagulant medication. ACTH, amphotericin B, corticosteroids increase hypokalemia risk. May increase toxicity of diazoxide, digitalis, lithium, verapamil, lidocaine. Antagonized by NSAIDs. Antagonizes methenamine, antigout drugs. May block epinephrine. May interfere with glaucoma, parathyroid screening tests.
Adverse Reactions:
Cardiac failure, bronchospasm, bradycardia, heart block, fatigue, fluid and electrolyte imbalance, orthostatic hypotension, GI upset, dizziness, blurred vision, cold extremities, rash, pruritus, blood dyscrasias.
How Supplied:
Tabs—100
Sign Up for Free e-newsletters
ONA Articles
- Real World Results May Not Mirror Clinical Study Outcomes in Multiple Myeloma
- Is Radioimmunotherapy a Path Forward for Melanoma?
- FDA Approves Mogamulizumab-kpkc for Rare Subtypes of Non-Hodgkin Lymphoma
- New PDL1 Inhibitors for Non-small Cell Lung Cancer: Focus on Pembrolizumab
- Intensive Chemotherapy May Not Be Effective in MDS or AML After MDS
- NCCIH HerbList App Launched to Provide Information on Herbal Products
- Metformin Use May Improve Survival Outcomes in Bladder Cancer
- Higher Vitamin D Levels Associated With Lower Breast Cancer Risk
- Nurse-Led Program Improves Health, Financial Outcomes in Outpatient Chemotherapy
- Seeking Reliable Information on Herbal Products
- 8 Hours of Bedrest May Be Ideal After Intrathecal Chemotherapy in Hematologic Cancers
- Adding Bevacizumab to First-line Chemotherapy Benefits Selects Cases of Ovarian Cancer
- Assessing Direct Costs of Treatment-Related Adverse Events in Advanced Melanoma
- New PDL1 Inhibitors for Non-small Cell Lung Cancer: Focus on Pembrolizumab
- Health Domains May Mediate Psychological Risk in Survivors of Childhood Leukemia
Regimen and Drug Listings
GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION
| Bone Cancer | Regimens | Drugs |
| Brain Cancer | Regimens | Drugs |
| Breast Cancer | Regimens | Drugs |
| Endocrine Cancer | Regimens | Drugs |
| Gastrointestinal Cancer | Regimens | Drugs |
| Genitourinary Cancer | Regimens | Drugs |
| Gynecologic Cancer | Regimens | Drugs |
| Head and Neck Cancer | Regimens | Drugs |
| Hematologic Cancer | Regimens | Drugs |
| Lung Cancer | Regimens | Drugs |
| Other Cancers | Regimens | |
| Rare Cancers | Regimens | |
| Skin Cancer | Regimens | Drugs |